Complexes of types of MHC class II that bind to collagen type II peptides and their use on diagnosis and treatment
US-10774129-B2 · Sep 15, 2020 · US
Oral composition
US9492494B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9492494-B2 |
| Application number | US-60259708-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 30, 2008 |
| Priority date | Jun 1, 2007 |
| Publication date | Nov 15, 2016 |
| Grant date | Nov 15, 2016 |
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- Title
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Abstract
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An object of the present invention is to provide an oral composition useful for promoting collagen synthesis and the like. The present invention can provide an oral composition containing collagen or gelatin or a degradation product thereof, and hydroxyproline or a salt thereof. The weight ratio of alanine and hydroxyproline contained in the amino acids obtained by hydrolyzing the oral composition is preferably 1:1.5-150.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of promoting collagen synthesis or reducing face dryness, comprising administering to a subject in need thereof an oral composition comprising (a) a composition of collagen or gelatin or a degradation product thereof, and (b) hydroxyproline or a salt thereof, wherein the weight ratio of (a):(b) in the oral composition is 1:0.2-5.0, the weight ratio of the free form of alanine to the free form of hydroxyproline obtained by hydrolyzing the oral composition is 1:3.5-60, the weight of hydroxyproline liberated by hydrolysis of the oral composition is 0.1-1 g, and the composition is in one or more discrete portions. 2. The method of claim 1 , wherein the oral composition is formed by adding hydroxyproline or a salt thereof to the composition of collagen or gelatin or a degradation product thereof. 3. The method of claim 1 , wherein the hydrolyzing is hydrolyzing with an acid or alkali. 4. A method of promoting collagen synthesis or reducing face dryness, comprising administering to a subject in need thereof an oral composition comprising (a) collagen or gelatin or a degradation product thereof, and (b) hydroxyproline or a salt thereof, wherein the weight ratio of (a):(b) in the oral composition is 1:0.2-5.0, the weight ratio of the free form of alanine to the free form of hydroxyproline obtained by hydrolyzing the oral composition is 1:3.5-60, the weight of hydroxyproline liberated by hydrolysis of the oral composition is 0.1-1 g, and the composition is in one or more discrete portions. 5. The method of claim 4 , wherein the oral composition is formed by adding hydroxyproline or a salt thereof to the collagen or gelatin or a degradation product thereof. 6. The method of claim 4 , wherein the hydrolyzing is hydrolyzing with an acid or alkali.
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Nutrients, e.g. vitamins, minerals · CPC title
Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title
Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG] · CPC title
Adding ingredients (adding preservatives A23B70/10) · CPC title
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- What does patent US9492494B2 cover?
- An object of the present invention is to provide an oral composition useful for promoting collagen synthesis and the like. The present invention can provide an oral composition containing collagen or gelatin or a degradation product thereof, and hydroxyproline or a salt thereof. The weight ratio of alanine and hydroxyproline contained in the amino acids obtained by hydrolyzing the oral composit…
- Who is the assignee on this patent?
- Kamimura Ayako, Sakai Yasushi, Ikeda Takeshi, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification A61K38/014. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Nov 15 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).