Copper(I) complexes for optoelectronic devices
US-9266906-B2 · Feb 23, 2016 · US
Gold(I) complexes with t-butyl phosphine and dialkyl dithiocarbamate ligands
US9492465B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9492465-B2 |
| Application number | US-201615042852-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 12, 2016 |
| Priority date | Mar 19, 2014 |
| Publication date | Nov 15, 2016 |
| Grant date | Nov 15, 2016 |
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Abstract
Official abstract text for this publication.
Gold(I) complexes of formulae [Au{P(t-Bu) 3 }(S 2 CN(CH 3 ) 2 )] (1), and [Au{P(t-Bu) 3 }(S 2 CN(C 2 H 5 ) 2 )] (2) have been prepared by the reaction of equimolar amounts of [Au{P(t-Bu) 3 }(Cl)] with sodium dimethyldithiocarbamate monohydrate, and sodium diethyldithiocarbamate trihydrate respectively. Both complexes (1) and (2) are iso-structural having linear geometry. These gold(I) dithiocarbamate complexes show in vitro cytotoxic activities against A549 (human lung carcinoma), HeLa (human cervical cancer) and MCF7 (human breast cancer) cell lines.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for treating cancer or a tumor comprising administering, in a cytotoxically effective amount, a gold complex of formula Au{P(t-Bu) 3 }(S 2 CN(R) 2 ) where R is CH 3 or C 2 H 5 to a subject in need of treatment for a human cervical cancer.
Assignees
Inventors
Classifications
- C07F9/5045Primary
Complexes or chelates of phosphines with metallic compounds or metals · CPC title
- A61K31/66Primary
Phosphorus compounds · CPC title
for testing antineoplastic activity · CPC title
involving specific cell types · CPC title
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- What does patent US9492465B2 cover?
- Gold(I) complexes of formulae [Au{P(t-Bu) 3 }(S 2 CN(CH 3 ) 2 )] (1), and [Au{P(t-Bu) 3 }(S 2 CN(C 2 H 5 ) 2 )] (2) have been prepared by the reaction of equimolar amounts of [Au{P(t-Bu) 3 }(Cl)] with sodium dimethyldithiocarbamate monohydrate, and sodium diethyldithiocarbamate trihydrate respectively. Both complexes (1) and (2) are iso-structural having linear geometry. These gold(I) dithiocar…
- Who is the assignee on this patent?
- Univ King Fahd Pet & Minerals, King Abdulaziz City Sci & Tech
- What technology area does this patent fall under?
- Primary CPC classification C07F9/5045. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 15 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).