Methods for assessing repellant quality of organic materials and methods and compositions for repelling arthropods

Patent metadata

Field	Value
Publication number	US-9491942-B2
Application number	US-201214352483-A
Country	US
Kind code	B2
Filing date	Oct 17, 2012
Priority date	Oct 17, 2011
Publication date	Nov 15, 2016
Grant date	Nov 15, 2016

Abstract

The disclosure provides compounds useful as insect repellents, compositions comprising such repellents, and methods of repelling an arthropod using such compounds and compositions. The disclosure further provides insect traps and method for identifying ligands and cognates for biological molecules.

First claim

What is claimed is:

1. A method of repelling an arthropod, comprising exposing the arthropod to a repelling composition, wherein the repelling composition comprises at least one compound of formula I:

wherein:
R 1 is selected from the group consisting of C6-C12 alkyl, C4-C12 alkenyl, aryl, and arylalkyl;
R 2 and R 3 are each independently selected from the group consisting of H, C1-C12 alkyl, benzoyl, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloakenylalkyl, arylalkyl, formyl, acyl, and R 2 and R 3 taken together form an ═C—R 8 ;
R 4 , R 5 , R 6 , and R 7 are each independently selected from the group consisting of H, C1-C4 alkyl, halo, and alkoxy; and
R 8 is selected from the group consisting of C1-C12 alkyl, C2-C12 alkenyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, cycloakenyl, and cycloakenylalkyl.

2. The method of claim 1 , wherein:
R 1 is selected from the group consisting of C6-C12 alkenyl, aryl, and arylalkyl;
R 2 and R 3 are each H; and
R 4 , R 5 , R 6 , and R 7 are each independently selected from the group consisting of H, C1-C4 alkyl, halo, and alkoxy.

3. The method of claim 1 , wherein the at least one compound of Formula 1 is

4. The method of claim 1 , wherein the at least one compound is

5. The method of claim 1 , wherein the at least one compound is

6. The method of claim 1 , wherein the repelling composition is applied on the body of one or more vertebrates or one or more plants to expose the repelling composition to the arthropod.

7. The method of claim 1 , wherein the repelling composition is formulated as a lotion, cream, dust, cosmetic, perfume, spray, paste, slow-release granule, paint, treated clothing, treated netting, treated building material, or incense.

8. The method of claim 1 , wherein the exposing the arthropod to the repelling composition is carried out using a vaporizer, evaporator, fan, heat, candle, or wicked apparatus.

9. The method of claim 1 , wherein the arthropod is of the order Diptera.

10. The method of claim 9 , wherein the arthropod is of the genus Drosophila.

11. The method of claim 1 , wherein the arthropod is a mosquito.

12. The method of claim 11 , wherein the mosquito is of the species Aedes aegypti.

13. A method of repelling an arthropod, comprising exposing the arthropod to a repelling composition, wherein the repelling composition comprises at least one compound selected from the group consisting of:

14. The method of claim 13 , wherein the at least one compound is selected from the group consisting of

15. The method of claim 13 , wherein the at least one compound is

16. The method of claim 13 , wherein the at least one compound is

17. The method of claim 13 , wherein the at least one compound is

18. The method of claim 13 , wherein the at least one compound is

19. The method of claim 13 , wherein the at least one compound is

20. The method of claim 13 , wherein the at least one compound is

21. The method of claim 13 , wherein the at least one compound is

22. The method of claim 13 , wherein the at least one compound is

23. The method of claim 13 , wherein the repelling composition is formulated as a lotion, cream, dust, cosmetic, perfume, spray, paste, slow-release granule, paint, treated clothing, treated netting, treated building material, or incense.

24. The method of claim 13 , wherein the exposing the arthropod to the repelling composition is carried out using a vaporizer, evaporator, fan, heat, candle, or wicked apparatus.

25. The method of claim 13 , wherein the arthropod is of the order Diptera.

26. The method of claim 25 , wherein the arthropod is of the genus Drosophila.

27. The method of claim 13 , wherein the arthropod is a mosquito.

28. The method of claim 27 , wherein the mosquito is of the species Aedes aegypti.

Assignees

• Univ California

Inventors

• Ray Anandasankar
• Boyle Sean Michael

Classifications

• A01N43/38

  condensed with carbocyclic rings · CPC title

• A01N37/36

  containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids · CPC title

• A01N43/54

  1,3-Diazines; Hydrogenated 1,3-diazines · CPC title

• A01N43/40

  six-membered rings · CPC title

• A01N37/10

  Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof · CPC title