Use of polypeptides with calcium indicator activity for identifying the activity of insecticidal proteins
US-2024426834-A1 · Dec 26, 2024 · US
Genetically encoded calcium indicators and methods of use
US9488642B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9488642-B2 |
| Application number | US-201514800814-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 16, 2015 |
| Priority date | Oct 10, 2012 |
| Publication date | Nov 8, 2016 |
| Grant date | Nov 8, 2016 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels and methods of monitoring neural activity also are provided.
First claim
Opening claim text (preview).
What is claimed is: 1. A GECI polypeptide, wherein the polypeptide comprises an amino acid sequence having at least 99% sequence identity to the sequence shown in SEQ ID NO:6. 2. The polypeptide of claim 1 , wherein the polypeptide comprises the amino acid sequence shown in SEQ ID NO:6. 3. A cell comprising a polypeptide of claim 1 .
Assignees
Inventors
Classifications
- G01N33/5041Primary
involving analysis of members of signalling pathways · CPC title
Calcium binding proteins, e.g. calmodulin · CPC title
containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP] · CPC title
involving cells · CPC title
Calcium binding proteins, e.g. calmodulin · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US9488642B2 cover?
- Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels and methods of monitoring neural activity also are provided.
- Who is the assignee on this patent?
- Hughes Howard Med Inst
- What technology area does this patent fall under?
- Primary CPC classification G01N33/5041. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Nov 08 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).