Systems and methods for detecting an analyte of interest in a sample using microstructured surfaces

US9488563B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9488563-B2
Application numberUS-201214122343-A
CountryUS
Kind codeB2
Filing dateJun 26, 2012
Priority dateJun 30, 2011
Publication dateNov 8, 2016
Grant dateNov 8, 2016

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Abstract

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Method for detecting an analyte of interest in a sample. The method can include providing a container comprising a microstructured surface, and centrifuging the container toward the microstructured surface to form a sediment and a supernatant of the sample. Following centrifugation, the container can be inverted to decant at least a portion of the supernatant of the sample from the second portion, such that a concentrate (e.g., comprising the sediment) of the sample is retained in the microstructured surface. The concentrate can then be interrogated in the microstructured surface for the analyte of interest. In some embodiments, at least a portion of the second portion can be substantially transparent, such that the concentrate can be interrogated from the outside of the container, without requiring that the container be opened prior to interrogation.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for interrogating a sample for an analyte of interest, the method comprising: providing a container adapted to contain the sample, the container comprising a microstructured surface configured to provide capillary forces to retain a sample of interest; centrifuging the container toward the microstructured surface to form a sediment and a supernatant of the sample; inverting the container, after centrifuging the container, to decant at least a po…

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What does patent US9488563B2 cover?
Method for detecting an analyte of interest in a sample. The method can include providing a container comprising a microstructured surface, and centrifuging the container toward the microstructured surface to form a sediment and a supernatant of the sample. Following centrifugation, the container can be inverted to decant at least a portion of the supernatant of the sample from the second porti…
Who is the assignee on this patent?
Halverson Kurt J, Rajagopal Raj, Kuduva Raman Thanumoorthy Ramasubramani, and 1 more
What technology area does this patent fall under?
Primary CPC classification B01L3/5021. Mapped technology areas include Operations & Transport.
When was this patent published?
Publication date Tue Nov 08 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).