Anti-CTLA-4 antibody compositions

US9487581B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9487581-B2
Application numberUS-81789406-A
CountryUS
Kind codeB2
Filing dateMar 2, 2006
Priority dateMar 8, 2005
Publication dateNov 8, 2016
Grant dateNov 8, 2016

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  2. Abstract

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Abstract

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The present invention provides for novel compositions of anti-CTLA-4 antibodies comprising a chelating agent. Also provided are method of treating diseases and conditions with novel compositions of CTLA-4 antibodies, including various neoplasia conditions.

First claim

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What is claimed is: 1. A composition comprising: a chelating agent at a concentration of about 0.01 mM to about 5.0 mM; histidine at a concentration of about 1 mM to about 100 mM; a surfactant at a concentration of about 0.01 mg/ml to about 10 mg/ml; trehalose at a concentration of about 100 mM to about 300 mM; and an antibody at a concentration of about 1 mg/ml to about 200 mg/ml, wherein said antibody binds to human CTLA-4 and comprises the heavy chain CDR1, CDR2, and CD…

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What does patent US9487581B2 cover?
The present invention provides for novel compositions of anti-CTLA-4 antibodies comprising a chelating agent. Also provided are method of treating diseases and conditions with novel compositions of CTLA-4 antibodies, including various neoplasia conditions.
Who is the assignee on this patent?
Abate Justin, Muthurania Kevin, Nema Sandeep, and 4 more
What technology area does this patent fall under?
Primary CPC classification C07K16/243. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Nov 08 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).