Fibronectin based scaffold domain proteins that bind IL-23
US-8927693-B2 · Jan 6, 2015 · US
US9487580B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9487580-B2 |
| Application number | US-201414228556-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 28, 2014 |
| Priority date | Oct 26, 2009 |
| Publication date | Nov 8, 2016 |
| Grant date | Nov 8, 2016 |
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Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
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What is claimed is: 1. An isolated antigen binding protein that binds IL-23, comprising: a CDRH1 of SEQ ID NO: 109; a CDRH2 of SEQ ID NO: 116; a CDRH3 of SEQ ID NO: 111; a CDRL1 of SEQ ID NO: 80; a CDRL2 of SEQ ID NO: 81; and a CDRL3 of SEQ ID NO: 76. 2. An isolated antigen binding protein that binds IL-23 comprising: a heavy chain variable region comprising amino acid residues 31-37, 52-67 and 100-109 of SEQ ID NO: 46 or 153; and a light chain var…
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