Incorporating an optical waveguide into a neural interface

Patent metadata

Field	Value
Publication number	US-9486641-B2
Application number	US-201414210260-A
Country	US
Kind code	B2
Filing date	Mar 13, 2014
Priority date	Mar 16, 2013
Publication date	Nov 8, 2016
Grant date	Nov 8, 2016

Abstract

An optical waveguide integrated into a multielectrode array (MEA) neural interface includes a device body, at least one electrode in the device body, at least one electrically conducting lead coupled to the at least one electrode, at least one optical channel in the device body, and waveguide material in the at least one optical channel. The fabrication of a neural interface device includes the steps of providing a device body, providing at least one electrode in the device body, providing at least one electrically conducting lead coupled to the at least one electrode, providing at least one optical channel in the device body, and providing a waveguide material in the at least one optical channel.

First claim

The invention claimed is:

1. A method of fabricating a neural interface device, comprising the steps of:
providing a multilayer device body having a first polymer layer with at least one opening,
providing at least one electrode in said at least one opening in said first polymer layer of said device body,
providing a second polymer layer of said multilayer device body that includes at least one electrically conducting lead coupled to said at least one electrode,
providing a third polymer layer of said multilayer device body that includes at least one optical channel,
providing a waveguide material in said at least one optical channel, and
providing a fourth polymer layer,
wherein said first polymer layer, said second polymer layer, said third polymer layer, and said fourth polymer layer are in a stacked relationship to each other and said first polymer layer provides a top of said multilayer device body and said fourth polymer layer provides a bottom of said multilayer device body.

2. The method of fabricating a neural interface device of claim 1 further comprising providing at least one electrical contact connected to said at least one electrically conducting lead.

3. The method of fabricating a neural interface device of claim 1 wherein said step of providing a multilayer device body comprises providing a multilayer polymer-based device body.

4. The method of fabricating a neural interface device of claim 1 wherein said step of providing a waveguide material in said at least one optical channel comprises providing a light conductive media in said at least one optical channel.

5. The method of fabricating a neural interface device of claim 1 wherein said step of providing a waveguide material in said at least one optical channel comprises providing a light conductive glass in said at least one optical channel.

6. The method of fabricating a neural interface device of claim 1 wherein said step of providing a waveguide material in said at least one optical channel comprises providing a light conductive polymer in said at least one optical channel.

7. The method of fabricating a neural interface device of claim 1 wherein said step of providing a waveguide material in said at least one optical channel comprises providing a light conductive water in said at least one optical channel.

8. The method of fabricating a neural interface device of claim 1 wherein said step of providing a waveguide material in said at least one optical channel comprises providing light conductive ink in said at least one optical channel.

9. The method of fabricating a neural interface device of claim 1 wherein said step of providing a waveguide material in said at least one optical channel comprises providing a light conductive saline solution in said at least one optical channel.

10. The method of fabricating a neural interface device of claim 1 wherein said step of providing at least one optical channel in said multilayer device body comprises providing at least one optical channel having light reflective walls.

11. The method of fabricating a neural interface device of claim 1 wherein said step of providing at least one optical channel in said multilayer device body comprises providing at least one optical channel having opaque walls.

12. A neural interface device having a multilayer device body, at least one electrode in said device body, at least one electrically conducting lead coupled to said at least one electrode, at least one optical channel in said device body, and waveguide material in said at least one optical channel produced by the process comprising the steps of:
providing a multilayer device body having a first polymer layer with at least one opening,
providing at least one electrode in said at least one opening in said first polymer layer of said device body,
providing a second polymer layer of said multilayer device body that includes at least one electrically conducting lead coupled to said at least one electrode,
providing a third polymer layer of said multilayer device body that includes at least one optical channel,
providing a waveguide material in said at least one optical channel, and
providing a fourth polymer layer,
wherein said first polymer layer, said second polymer layer, said third polymer layer, and said fourth polymer layer are in a stacked relationship to each other and said first polymer layer provides a top of said multilayer device body and said fourth polymer layer provides a bottom of said multilayer device body.

13. The neural interface device of claim 12 wherein said waveguide material is a light conductive media.

14. The neural interface device of claim 12 wherein said waveguide material is a light conductive media and wherein said at least one optical channel is a reflective channel.

15. The neural interface device of claim 12 wherein said at least one optical channel has walls that are reflective.

16. The neural interface device of claim 12 wherein said at least one optical channel has walls that are opaque.

17. The neural interface device of claim 12 wherein said waveguide material is glass.

18. The neural interface device of claim 12 wherein said waveguide material is a polymer.

19. The neural interface device of claim 12 wherein said waveguide material is saline.

20. The neural interface device of claim 12 wherein said waveguide material is water.

Assignees

• L Livermore Nat Security Llc

Inventors

• Tolosa Vanessa
• Delima Terri L
• Felix Sarah H
• Pannu Satinderpall S
• Shah Kedar G
• Sheth Heeral
• Tooker Angela C

Classifications

• A61N1/0529

  Electrodes for brain stimulation · CPC title

• A61N2005/0612

  using probes penetrating tissue; interstitial probes · CPC title

• A61B2090/571

  for clamping a support arm to a bed or other supports · CPC title

• A61N2005/063

  comprising light transmitting means, e.g. optical fibres · CPC title

• A61B2562/12

  Manufacturing methods specially adapted for producing sensors for in-vivo measurements · CPC title