Hydrophilic AIOL with bonding

Patent metadata

Field	Value
Publication number	US-9486311-B2
Application number	US-201414181145-A
Country	US
Kind code	B2
Filing date	Feb 14, 2014
Priority date	Feb 14, 2013
Publication date	Nov 8, 2016
Grant date	Nov 8, 2016

Abstract

An accommodating intraocular lens comprises a first lens component, a second lens component, and an adhesive between portions of the two lens components. The cured adhesive bonds the lens components to form a fluid chamber. The lens components are bonded to one another along a seam which extends circumferentially along at least a portion of the lens components. The lens components may comprise the same polymer material. The cured adhesive also comprises the polymer or a prepolymer of the polymer to provide increased strength. The polymer is hydratable such that the lens components and the cured adhesive therebetween can swell together to inhibit stresses between the lens components and the cured adhesive.

First claim

What is claimed is:

1. A method of manufacturing an accommodating intraocular lens, the method comprising:
providing a first lens component comprising a polymer, the first lens component comprising a first inner surface region extending discontinuously and circumferentially around a center of the first lens component and a first outer surface region extending circumferentially around the first inner surface region;
providing a second lens component comprising the polymer, the second lens component comprising a second inner surface region extending discontinuously and circumferentially around a center of the second lens component and a second outer surface region extending circumferentially around the second inner surface region;
bonding the first inner and outer surface regions of the first lens component to the second inner and outer surface regions of the second lens component with an adhesive comprising a prepolymer of the polymer, wherein the prepolymer is cured to bond the first lens component to the second lens component with the cured prepolymer extending between the first and second inner surface regions and between the first and second outer surface regions; thereby creating an inner seam and an outer seam, respectively, the inner seam defining an inner fluid chamber enclosed therewithin and the inner and outer seams defining an outer haptic chamber enclosed therebetween, the outer haptic chamber being in fluid communication with the inner fluid chamber; and
hydrating the bonded first lens component, the second lens component, and the cured prepolymer to provide a hydrated, soft accommodating intraocular lens comprising the polymer.

2. A method as in claim 1 , wherein the first lens component and the second lens component each comprise a stiff configuration when the first lens component is bonded to the second lens component, with the cured prepolymer at the inner and outer seams extending between the first lens component and the second lens component.

3. A method as in claim 1 , wherein hydrating the first lens component, the second lens component and the adhesive comprises fully hydrating the polymer of each of the components and the adhesive to an amount of hydration corresponding to an amount of hydration of the polymer when implanted.

4. A method as in claim 1 , wherein each of the first lens component, the second lens component, and the cured adhesive each comprise a stiff configuration prior to hydration and a soft configuration when hydrated and wherein each of the first lens component, the second lens component, and the cured adhesive expand a substantially similar amount from the stiff configuration to the soft configuration in order to inhibit stress at interfaces between the adhesive and the first and second components.

5. A method as in claim 1 , further comprising providing the polymer material and shaping the first lens component and the second lens component from the polymer material.

6. A method as in claim 5 , wherein the first lens component and the second lens component are each turned on a lathe when stiff in order to shape the first lens component and the second lens component.

7. A method as in claim 5 , wherein the first lens component and the second lens component are molded.

8. A method as in claim 1 , wherein the prepolymer comprises one or more of a monomer, an oligomer, a partially cured monomer, particles, or nano particles of the polymer.

9. A method as in claim 1 , wherein the first lens component comprises a first disc shaped structure, which includes the first inner surface region, and the second lens component comprises a second disc shaped structure, which includes the second inner surface region, and wherein the first component and the second component define the inner fluid chamber with the first and second disc shaped structures on opposite sides of the inner fluid chamber when bonded together.

10. A method as in claim 9 , wherein one or more of the first lens component or the second lens component comprises an annular structure or an array of circumferentially distributed structures extending between the first disc structure and the second disc structure in order to separate the first disc structure from the second disc structure and define a side wall separating the inner fluid chamber from the outer haptic chamber.

11. A method as in claim 1 , wherein one or more of the first inner surface region of the first lens component or the second inner surface region of the second lens component comprises a groove sized and shaped to receive the opposite inner surface, and wherein the adhesive is placed on the groove.

12. A method as in claim 1 , wherein one or more of the first outer surface region of the first component or the second outer surface region of the second component comprises a groove sized and shaped to receive the opposite outer surface, and wherein the adhesive is placed on the groove.

13. A method as in claim 1 , wherein both the first and second outer surface regions extend continuously circumferentially therearound to define the outer haptic chamber.

14. A method as in claim 1 , further comprising filling one or more of the inner fluid chamber or outer haptic chamber with a fluid.

15. A method as in claim 14 , wherein the fluid comprises one or more of a solution, an oil, a silicone oil, a solution of high molecular weight molecules, or high molecular weight dextran.

16. A method as in claim 14 , wherein the fluid has an index of refraction greater than an index of refraction of an aqueous humor of an eye.

Assignees

• Shifamed Holdings Llc

Inventors

• Argento Claudio
• Vaughan Bob
• Salahieh Amr
• Saul Tom

Classifications

• A61F2002/169

  Surrounding optic · CPC title

• A61F2/1635

  for changing shape · CPC title

• B29D11/023

  Implants for natural eyes · CPC title

• B29D11/00028

  Bifocal lenses; Multifocal lenses · CPC title

• B29C65/483

  Reactive adhesives, e.g. chemically curing adhesives · CPC title