Compositions, Devices, Systems, and Methods for Using a Nanopore
US-2016040230-A1 · Feb 11, 2016 · US
Compositions, devices, systems, and methods for using a nanopore
US9481908B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9481908-B2 |
| Application number | US-201414192785-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 27, 2014 |
| Priority date | Apr 4, 2007 |
| Publication date | Nov 1, 2016 |
| Grant date | Nov 1, 2016 |
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Abstract
Official abstract text for this publication.
The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore in the absence of requiring a terminating nucleotide. The devices and methods are also used to determine rapidly (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of drug discovery, molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.
First claim
Opening claim text (preview).
What is claimed is: 1. A method for controlling movement of a polynucleotide using voltage control, the method resulting in identifying a sequence of a polynucleotide, the method comprising the steps of: a) providing two separate adjacent chambers comprising a medium, an interface between the two chambers, the interface comprising a material having at least one channel therethrough and wherein one chamber is on the cis-side of the interface and the other chamber is on the trans-si…
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Classifications
- C12Q1/6874Primary
Chemistry & Metallurgy · mapped topic
- C12Q1/6869Primary
Chemistry & Metallurgy · mapped topic
Physics · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US9481908B2 cover?
- The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore in the absence of requiring a terminating nucleotide. The devices and methods are also used to determine rapidly (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or…
- Who is the assignee on this patent?
- Univ California
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6874. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 01 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).