Apparatus and methods for lipidic cubic phase (LCP) injection for membrane protein investigations
US-9821325-B2 · Nov 21, 2017 · US
US9480994B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9480994-B2 |
| Application number | US-201314385542-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 5, 2013 |
| Priority date | Mar 21, 2012 |
| Publication date | Nov 1, 2016 |
| Grant date | Nov 1, 2016 |
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Disclosed is a shower apparatus comprising: •a housing ( 1, 2, 3 ) for an object ( 4 ); and •a plurality of set of coplanar nozzles inside said housing, the nozzles allowing for a simultaneous spray of a pressurized gas and a liquid on said object. Each set of nozzles comprises a first nozzle ( 7 a, 7 b, 7 c ) for spraying for spraying said gas and adjacent thereto at least one further nozzle ( 6 a, 6 b, 6 c, 8 a, 8 b, 8 c ) for spraying said liquid. The axis of the nozzle for spraying said gas is arranged at an acute angle with respect to the axis of the nozzle for spraying said liquid. The nozzles are configured to provide improved cleansing in a single shower while consuming less water.
Opening claim text (preview).
The invention claimed is: 1. A shower apparatus comprising a housing for an object ( 4 ), characterised in that the apparatus also comprises a plurality of sets of coplanar nozzles inside said housing, for a simultaneous spray of a pressurized gas and a liquid on said object; wherein each set comprises: (i) a nozzle ( 7 a , 7 b , 7 c ) for spraying said gas; and (ii) adjacent thereto, at least one nozzle ( 6 a , 6 b , 6 c ) for spraying said liquid, and wherein the tip of said nozzle ( 7 a , 7 b , 7 c ) for spraying said gas is at an acute angle (X) with the tip of each nozzle ( 6 a , 6 b , 6 c ) for spraying said liquid. 2. A shower apparatus as claimed in claim 1 wherein each said set comprises three nozzles: (i) a middle nozzle ( 7 a , 7 b , 7 c ) for spraying said gas; and, (ii) two nozzles ( 6 a , 6 b , 6 c , 8 a , 8 b , 8 c ) adjacent thereto, one each on either side thereof, for spraying said liquid, wherein the tip of each of said middle nozzle ( 7 a , 7 b , 7 c ) is at an acute angle (X) with the tip of each of said two nozzles ( 6 a , 6 b , 6 c , 8 a , 8 b , 8 c ). 3. A shower apparatus as claimed in claim 1 wherein the tip of said nozzle for spraying said gas terminates a distance of upto 0.4 cm before or upto 1 cm ahead of tip of each nozzle for spraying said liquid. 4. A shower apparatus as claimed in claim 1 wherein the distance between said plurality of sets of coplanar nozzles and said object is 7.62 cm to 45.72 cm or 3 inches to 18 inches. 5. A shower apparatus as claimed in claim 1 wherein operating pressure of said gas is 2 bar to 8 bar. 6. A shower apparatus as claimed in claim 1 wherein said acute angle is 20° to 60°. 7. A shower apparatus as claimed in claim 1 wherein internal diameter of each said nozzle is 0.5 mm to 0.8 mm. 8. A shower apparatus as claimed in claim 1 wherein said plurality of set of nozzles is movable in one or more directions relative to said object. 9. A shower apparatus as claimed in claim 1 , comprising ten to hundred set of nozzles. 10. A shower apparatus as claimed in claim 1 comprising plurality of pipes forming a ring around said object wherein said nozzles are located on said pipes. 11. A shower apparatus as claimed in claim 10 wherein each said pipe comprises ten to hundred nozzles. 12. A shower apparatus as claimed in claim 10 comprising at least one group of three pipes comprising a middle pipe having nozzles thereon to spray said gas and two adjacent pipes, one on either side thereof, each having nozzles thereon to spray said liquid. 13. A shower apparatus as claimed in claim 10 wherein flow-rate of the liquid is 100 to 300 ml/minute. 14. A shower apparatus as claimed in claim 10 wherein temperature of the liquid is from 10° C. to 60° C. 15. A shower apparatus as claimed in claim 10 wherein said apparatus provides one shower in one to two minutes.
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