Marine based cosmetic active ingredients and use thereof

Patent metadata

Field	Value
Publication number	US-9480864-B2
Application number	US-201213588210-A
Country	US
Kind code	B2
Filing date	Aug 17, 2012
Priority date	Aug 17, 2011
Publication date	Nov 1, 2016
Grant date	Nov 1, 2016

Abstract

The present invention relates to a cosmetic and/or pharmaceutical active component for stimulating proteasome activity of skin cells comprising the broth obtained by inoculating a biomass of the algae, Gracilaria spp., particularly the algae, Gracilaria tikvahiae , with a yeast culture, and allowing fermentation of the biomass to produce a fermentation broth. Also described is a cosmetic and/or pharmaceutical active component for stimulating proteasome activity of skin cells comprising an extract of the algae, Gracilaria tikvahiae . The present invention also relates to topical compositions comprising as a cosmetic and/or pharmaceutical active component a ferment of the algae, Gracilaria spp., particularly the algae, Gracilaria tikvahiae , or an extract of the algae, Gracilaria tikvahiae , or a combination of both.

First claim

What is claimed is:

1. A topical composition for increasing proteasome activity in fibroblasts of human skin comprising an effective amount of a fermentation broth obtained by inoculating a biomass of algae of the species Gracilaria and a live yeast culture within a broth and fermenting the broth for a suitable time, wherein the effective amount of said fermentation broth is in the range of about 0.1% to 5% by weight based on the final weight of the composition.

2. The topical composition of claim 1 wherein the topical composition comprises between about 0.01% and about 10% by weight of the cosemetic active component.

3. The topical composition of claim 1 , wherein the yeast is Saccharomyces cerevisae.

4. The topical composition of claim 1 , wherein the yeast is Zygosaccharomyces rouxii.

5. The topical composition of claim 1 , comprising an additional cosmetic active component wherein the second cosmetic active component is derived from a marine plant or animal.

6. The topical composition of claim 1 , wherein the Gracilaria species is Gracilaria tikvahiae.

7. The topical composition of claim 1 , wherein the Gracilaria species is Gracilaria gracilis.

8. The topical composition of claim 1 , wherein the Gracilaria species is Gracilaria parvispora.

9. The topical composition of claim 1 , wherein the Gracilaria species is Gracilaria vermiculophylia.

10. The topical composition of claim 1 , wherein the composition further comprises at least one ingredient selected from the group consisting of preservatives, emollients, emulsifying agents, surfactants, moisturizers, gelling agents, thickening agents, conditioning agents, film-forming agents, stabilizing agents, anti-oxidants, texturizing agents, gloss agents, mattifying agents, solubilizers, pigments, dyes, and fragrances.

11. The topical composition of claim 1 , further comprising an additional cosmetic active component which increases, stimulates and/or modulates proteasome activity in the skin.

12. The topical composition of claim 11 , wherein the additional cosmetic active component is derived from a marine plant.

13. The topical composition of claim 11 , wherein the topical composition comprises between about 1% and about 5% by weight of the fermentation broth based on the final weight of the composition and the yeast is Saccharomyces cerevisa or Zygosaccharomyces rouxii.

14. The topical composition of claim 13 , wherein the additional cosmetic active component is derived from a marine plant.

15. The topical composition of claim 1 , wherein the topical composition comprises between about 1% and 3% by weight of the fermentation broth based on the final weight of the composition.

16. The topical composition of claim 15 , wherein the yeast is Saccharomyces cerevisa.

17. The topical composition of claim 15 , wherein the yeast is Zygosaccharomyces rouxii.

Assignees

• Chavan Manasi
• Sun Yuhua
• Williams Christine
• Sunkin Michael
• Basf Corp

Inventors

• Chavan Manasi
• Sun Yuhua
• Williams Christine
• Sunkin Michael

Classifications

• A61K2800/85

  Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine · CPC title

• C12N1/12

  Unicellular algae; Culture media therefor (as new plants A01H13/00) · CPC title

• A61Q19/08 Primary

  Anti-ageing preparations · CPC title

• C12N1/18

  Baker's yeast; Brewer's yeast · CPC title

• C12P1/02 Primary

  by using fungi · CPC title