Robust polymeric membrane

Patent metadata

Field	Value
Publication number	US-9469737-B2
Application number	US-201414464201-A
Country	US
Kind code	B2
Filing date	Aug 20, 2014
Priority date	Aug 20, 2014
Publication date	Oct 18, 2016
Grant date	Oct 18, 2016

Abstract

Hydrophilic porous membranes comprising a random copolymer of:
(a) 2-hydroxyethyl methacrylate of formula (I):

(b) an ethylene glycol dimethacrylate of formula (II):

and
(c) 1,1,1-trimethylolpropane trimethacrylate of formula (III):

and a hydrophobic polymer; filters including the membranes, and methods of making and using the membranes, are disclosed.

First claim

The invention claimed is:

1. A hydrophilic microporous membrane comprising a polymer blend comprising a hydrophobic polymer and a random copolymer of:
(a) 2-hydroxyethyl methacrylate of formula (I):

(b) polyethylene glycol-400 dimethacrylate; and
(c) 1,1,1-trimethylolpropane trimethacrylate of formula (III):

wherein the hydrophilic microporous membrane is prepared by casting a polymer solution comprising the polymer blend onto a substrate before carrying out phase inversion of the polymer solution to provide the hydrophilic microporous membrane.

2. A hydrophilic microporous membrane prepared by a process comprising polymerizing in a solvent:
(a) 2-hydroxyethyl methacrylate of formula (I):

(b) polyethylene glycol-400 dimethacrylate; and
(c) 1,1,1-trimethylolpropane trimethacrylate of formula (III):

to form a random copolymer of (a), (b), and (c); wherein the solvent also includes (d) at least one initiator and (e) a hydrophobic polymer, before casting a solution comprising the random copolymer and the solvent onto a substrate, and carrying out phase inversion of the solution to provide the hydrophilic microporous membrane.

3. A hydrophilic microporous membrane prepared by a process comprising dissolving or dispersing in a solvent:
(a) 2-hydroxyethyl methacrylate of formula (I):

(b) polyethylene glycol-400 dimethacrylate;
(c) 1,1,1-trimethylolpropane trimethacrylate of formula (III):

(d) a hydrophic polymer; and,
(e) at least one initiator;
wherein each of (a)-(e) is dissolved or dispersed in the solvent in any order, or simultaneously;
and,
polymerizing (a), (b), and (c) to form a random copolymer of (a), (b), and (c), before casting a solution comprising the random copolymer and the solvent onto a substrate, and carrying out phase inversion of the solution to provide the hydrophilic microporous membrane.

4. The hydrophilic membrane of claim 1 , wherein the hydrophobic polymer is a sulfone polymer.

5. A method of filtering a fluid, the method comprising passing the fluid through the membrane of claim 1 .

6. The method of claim 5 , wherein the fluid is a protein-containing fluid.

7. The hydrophilic membrane of claim 2 , wherein the hydrophobic polymer is a sulfone polymer.

8. The hydrophilic membrane of claim 3 , wherein the hydrophobic polymer is a sulfone polymer.

9. A method of filtering a fluid, the method comprising passing the fluid through the membrane of claim 2 .

10. A method of filtering a fluid, the method comprising passing the fluid through the membrane of claim 3 .

11. A method of filtering a fluid, the method comprising passing the fluid through the membrane of claim 4 .

12. The method of claim 9 , wherein the fluid is a protein-containing fluid.

13. The method of claim 10 , wherein the fluid is a protein-containing fluid.

14. The method of claim 11 , wherein the fluid is a protein-containing fluid.

Assignees

• Pall Corp

Inventors

• Heidenreich Erik M
• Liang Xuemei
• Han Binbing

Classifications

• B01D2323/02

  Hydrophilization · CPC title

• C08F283/00

  Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G · CPC title

• B01D71/76

  Macromolecular material not specifically provided for in a single one of groups B01D71/08 - B01D71/74 (rubbers in general B01D71/24) · CPC title

• B01D39/1692

  Other shaped material, e.g. perforated or porous sheets · CPC title

• B01D71/68

  Polysulfones; Polyethersulfones · CPC title