Method of treating pancreatic cancer
US-2024415804-A1 · Dec 19, 2024 · US
US9468623B1 · US · B1
| Field | Value |
|---|---|
| Publication number | US-9468623-B1 |
| Application number | US-201615099621-A |
| Country | US |
| Kind code | B1 |
| Filing date | Apr 15, 2016 |
| Priority date | Apr 17, 2015 |
| Publication date | Oct 18, 2016 |
| Grant date | Oct 18, 2016 |
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The present invention provides compound extracted from Garcinia species and the use of said compound in preventing and treating cancer.
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The invention claimed is: 1. A method of treating metastasis of esophageal cancer comprising administering a composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt, prodrug or hydrate thereof. 2. The method of claim 1 , wherein the composition consists essentially of said compound of Formula (I), or said pharmaceutically acceptable salt, prodrug or hydrate thereof. 3. The method of claim 1 , wherein said esophageal cancer is selected from human esophageal carcinoma cell Eca109 and human esophageal cancer cells KYSE150. 4. The method of claim 1 , wherein said metastasis of esophageal cancer is lung metastasis. 5. The method of claim 1 , wherein the composition comprises 1.62 mg of a compound of Formula (I), or a pharmaceutically acceptable salt, prodrug or hydrate thereof per kg of a subject in need thereof. 6. A method of treating esophageal cancer comprising administering a composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt, prodrug or hydrate thereof. 7. The method of claim 6 , wherein the composition consists essentially of said compound of Formula (I), or said pharmaceutically acceptable salt, prodrug or hydrate thereof. 8. The method of claim 6 , wherein said esophageal cancer is selected from human esophageal carcinoma cell Eca109 and human esophageal cancer cells KYSE150. 9. The method of claim 6 , wherein the composition comprises 1.62 mg of a compound of Formula (I), or a pharmaceutically acceptable salt, prodrug or hydrate thereof per kg of a subject in need thereof.
Antineoplastic agents · CPC title
specific for metastasis · CPC title
Drugs for disorders of the alimentary tract or the digestive system · CPC title
condensed with carbocyclic rings, e.g. methantheline {(cannabinoids A61K31/658)} · CPC title
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