A polymeric system for release of an active agent
US-2015374838-A1 · Dec 31, 2015 · US
US9463262B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9463262-B2 |
| Application number | US-201113882857-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 1, 2011 |
| Priority date | Nov 4, 2010 |
| Publication date | Oct 11, 2016 |
| Grant date | Oct 11, 2016 |
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Official abstract text for this publication.
An object of the present invention is to provide a cell-adhesive material for biological tissues, in which the surface of a material for biological tissues (particularly metallic material) is modified strongly with a large amount of a cell-adhesive artificial peptide (P) that retains a biological activity. The present invention provides a cell-adhesive material for biological tissues including a cell-adhesive artificial peptide (P) and a material for biological tissues, wherein the cell-adhesive artificial peptide (P) is immobilized on the surface of the material for biological tissues through an electrochemical reaction. The cell-adhesive artificial peptide (P) is preferably a peptide (P1) that is synthesized by a genetic recombinant microorganism and has at least one cell-adhesive minimal amino acid sequence (X) in one molecule. The number of the cell-adhesive minimal amino acid sequences (X) in one molecule of the polypeptide (P1) is preferably 3 to 50.
Opening claim text (preview).
The invention claimed is: 1. A cell-adhesive substrate for biological tissues, comprising: a cell-adhesive artificial peptide (P), and a substrate for biological tissues, wherein the cell-adhesive artificial peptide (P) is immobilized on the surface of the substrate for biological tissues through an electrochemical reaction, wherein the cell-adhesive artificial peptide (P) is a polypeptide (P1) which is synthesized using a genetic recombinant microorganism and has at least o…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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