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Recombinant viral vectors and methods for inducing a heterosubtypic immune response to influenza A viruses
US9463237B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9463237-B2 |
| Application number | US-201213982524-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 30, 2012 |
| Priority date | Jan 31, 2011 |
| Publication date | Oct 11, 2016 |
| Grant date | Oct 11, 2016 |
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Abstract
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The present invention relates to recombinant viral vectors and methods of using the recombinant viral vectors to induce an immune response to influenza A viruses. The invention provides recombinant viral vectors based, for example, on the non-replicating modified vaccinia virus Ankara. When administered according to methods of the invention, the recombinant viral vectors are designed to be cross-protective and induce heterosubtypic immunity to influenza A viruses.
First claim
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We claim: 1. A recombinant modified vaccinia virus Ankara (rMVA) comprising a first gene cassette encoding an influenza A headless hemagglutinin (hlHA) polypeptide of SEQ ID NO: 15 and a second gene cassette encoding influenza A nucleoprotein (NP). 2. A pharmaceutical composition comprising the rMVA of claim 1 . 3. A method of inducing a heterosubtypic immune response to influenza A viruses in an individual comprising administering a pharmac…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US9463237B2 cover?
- The present invention relates to recombinant viral vectors and methods of using the recombinant viral vectors to induce an immune response to influenza A viruses. The invention provides recombinant viral vectors based, for example, on the non-replicating modified vaccinia virus Ankara. When administered according to methods of the invention, the recombinant viral vectors are designed to be cros…
- Who is the assignee on this patent?
- Falkner Falko-Günter, Schafer Birgit, Barrett P Noel, and 5 more
- What technology area does this patent fall under?
- Primary CPC classification C12N15/86. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Oct 11 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).