Trk-INHIBITING COMPOUND
US-2015111865-A1 · Apr 23, 2015 · US
US9463192B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9463192-B2 |
| Application number | US-201414768727-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 18, 2014 |
| Priority date | Feb 19, 2013 |
| Publication date | Oct 11, 2016 |
| Grant date | Oct 11, 2016 |
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Official abstract text for this publication.
The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.
Opening claim text (preview).
The invention claimed is: 1. The compound of 1-{2-[4-(2-amino-5-chloro-3-pyridinyl)phenoxy]-5-pyrimidinyl}-3-[2-(methylsulfonyl)-5-(trifluoromethyl)phenyl]urea or a salt thereof. 2. The compound of 1-{2-[4-(2-amino-5-chloro-3-pyridinyl)phenoxy]-5-pyrimidinyl}-3-[2-(methylsulfonyl)-5-(trifluoromethyl)phenyl]urea.
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca · CPC title
Ortho-condensed systems · CPC title
linked by a chain containing hetero atoms as chain links · CPC title
not condensed and containing further heterocyclic rings, e.g. timolol · CPC title
having the amino group directly attached to the aromatic ring, e.g. benzeneamine · CPC title
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