Differentiated human embryoid cells and a method for producing them

US9458425B1 · US · B1

Patent metadata
FieldValue
Publication numberUS-9458425-B1
Application numberUS-97900100-A
CountryUS
Kind codeB1
Filing dateMay 12, 2000
Priority dateMay 14, 1999
Publication dateOct 4, 2016
Grant dateOct 4, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A process for obtaining human derived embryoid bodies (hEB). Human embryonic stem cells are incubated in vitro in a liquid growth medium under conditions in which the cells undergo differentiation, but do not adhere to the walls of the container. The invention also provides hEBs obtained by the process.

First claim

Opening claim text (preview).

The invention claimed is: 1. A process for obtaining at least one human-derived embryoid body (hEB), comprising: (a) providing human embryonic stem (hES) cells; (b) growing the hES cells in vitro suspended in a liquid growth medium in a vessel under conditions under which said cells undergo differentiation and said cells or aggregates thereof do not adhere to the vessel wall, wherein said conditions comprise culturing cells in a vessel having walls of a kind to which cells do not adhere; and (c) incubating for a time sufficient to develop hEBs from said cells.

Assignees

Inventors

Classifications

  • Cardiomyocytes; Heart cells · CPC title

  • Pluripotent embryonic cells, e.g. embryonic stem cells [ES] (embryonic germ cells C12N5/0611, induced pluripotent stem cells C12N5/0696) · CPC title

  • Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

  • C12N5/0603Primary

    Embryonic cells (production of embryos, nuclear transfer A01K67/027); Embryoid bodies · CPC title

  • Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells (vaccines or medicinal preparations containing antigens or antibodies A61K39/00) · CPC title

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What does patent US9458425B1 cover?
A process for obtaining human derived embryoid bodies (hEB). Human embryonic stem cells are incubated in vitro in a liquid growth medium under conditions in which the cells undergo differentiation, but do not adhere to the walls of the container. The invention also provides hEBs obtained by the process.
Who is the assignee on this patent?
Itskovitz-Eldor Joseph, Benvenisty Nissim, Technion Res & Dev Foundation, and 1 more
What technology area does this patent fall under?
Primary CPC classification C12N5/0603. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).