Using mixtures of E/Z isomers to obtain quantitatively specific products by combined asymmetric hydrogenations

US9458076B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9458076-B2
Application numberUS-201314652339-A
CountryUS
Kind codeB2
Filing dateDec 18, 2013
Priority dateDec 18, 2012
Publication dateOct 4, 2016
Grant dateOct 4, 2016

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  1. Title

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  2. Abstract

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention relates to a process of manufacturing compound having stereogenic centers from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centers. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

First claim

Opening claim text (preview).

The invention claimed is: 1. A process of manufacturing a compound of formula (I-A) or (I-B) or an acetal or a ketal thereof from a mixture of E/Z isomers of compound of formula (I) or (II) or an acetal or a ketal thereof: wherein Q stands for H or CH 3 and m and p stand independently from each other for a value of 0 to 3 with the proviso that the sum of m and p is 0 to 3, and…

Assignees

Inventors

Classifications

  • Chemistry & Metallurgy · mapped topic

  • C07C45/62Primary

    Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

  • Chemistry & Metallurgy · mapped topic

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What does patent US9458076B2 cover?
The present invention relates to a process of manufacturing compound having stereogenic centers from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centers. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chira…
Who is the assignee on this patent?
Dsm Ip Assets Bv
What technology area does this patent fall under?
Primary CPC classification C07C45/62. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Oct 04 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).