Systems and methods for broad line fundus imaging

Patent metadata

Field	Value
Publication number	US-9456746-B2
Application number	US-201414207229-A
Country	US
Kind code	B2
Filing date	Mar 12, 2014
Priority date	Mar 15, 2013
Publication date	Oct 4, 2016
Grant date	Oct 4, 2016

Abstract

Systems and methods for Broad Line Fundus Imaging (BLFI), an imaging approach that is a hybrid between confocal and widefield imaging systems, are presented. These systems and methods are focused on improving the quality and signal of broad line fundus images or imaging methods to create high contrast and high resolution fundus images. Embodiments related to improved pupil splitting, artifact removal, reflex minimization, adaptable field of view, instrument alignment and illumination details are considered.

First claim

What is claimed:

1. A method for collecting reduced artifact images of the fundus of the eye with a broad line fundus imaging (BLFI) system, said method comprising;
scanning a beam of radiation over a range of transverse locations on the fundus of the eye, wherein the beam of radiation illuminates with a defined width on a region of the sample;
collecting light returning from the eye in response to the illumination, wherein the region on the sample from which light is collected corresponds to the illumination area and has a defined collection width, wherein the width of the illumination light and/or the width of the collection area is adjusted during the scanning steps;
generating an image from the collected light; and
displaying or storing the image.

2. A method as recited in claim 1 , wherein the illumination width is determined by one or more of the following: passing light through a slit, reflecting light from a mirror with a finite width, varying the extent of the light source.

3. A method as recited in claim 1 , wherein the collection width is determined by one or more of the following: passing light through a slit, reflecting light from a mirror with a finite width, and active area of a detector.

4. A method as recited in claim 1 , wherein the light is collected in a de-scanned configuration.

5. A method as recited in claim 1 , wherein the light is collected in a non-de-scanned configuration.

6. A method for collecting reduced artifact images of the fundus of the eye with a broad line fundus imaging (BLFI) system, said method comprising:
(a) scanning a beam of radiation over a range of transverse locations on the fundus of the eye;
(b) collecting light returning from the eye;
(c) scanning the beam of radiation over approximately the same range as when it was scanned over the eye;
(d) collecting light reflected from the optical components in the system without collecting light returning from the eye;
(e) subtracting the light collected at each transverse location in step d from the light collected at each transverse location in step b;
(f) generating an image from the result of the subtraction; and
(g) displaying or storing the image.

7. A method as recited in claim 6 , wherein step d precedes step b.

8. A method as recited in claim 6 , wherein step d is performed at the time the imaging system is manufactured.

9. A method as recited in claim 6 , wherein step d is performed just before or after step b.

10. A method as recited in claim 6 , wherein step d includes blocking light from reaching the eye.

11. A method as recited in claim 6 , wherein step d includes acquiring an image when light is not present.

Assignees

• Zeiss Carl Meditec Inc
• Zeiss Carl Meditec Ag

Inventors

• Bublitz Daniel
• Everett Matthew J
• Farkas Csaba
• Kempe Michael
• Qiu Yue
• Schmitt-Manderbach Tobias

Classifications

• A61B3/12

  for looking at the eye fundus, e.g. ophthalmoscopes (A61B3/13 takes precedence) · CPC title

• G02B21/0028

  specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes · CPC title

• A61B3/1025 Primary

  for confocal scanning · CPC title

• G02B21/0032

  Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers (G02B21/0036 - G02B21/008; means for illumination of specimens in general G02B21/06) · CPC title

• A61B3/14 Primary

  Arrangements specially adapted for eye photography · CPC title