Column heater with active pre-heating

Patent metadata

Field	Value
Publication number	US-9453824-B2
Application number	US-201113519818-A
Country	US
Kind code	B2
Filing date	Jan 11, 2011
Priority date	Jan 11, 2010
Publication date	Sep 27, 2016
Grant date	Sep 27, 2016

Abstract

To heat a flowing liquid, an apparatus includes a heater block assembly having a heater block made of thermally conductive material. The heater block assembly has a tube inlet, a tube outlet, and a tube path between the tube inlet and tube outlet. Tubing extends through the tube path from the tube inlet to the tube outlet. The tubing is in thermal communication with the heater block. A heater cartridge, in thermal communication with the heater block, is configured to provide heat to the heater block for transfer to liquid flowing through the tubing between the tube inlet and the tube outlet of the heater block assembly. Circuitry is in electrical communication with the heater cartridge to control a temperature of the heater block by controlling operation of the heater cartridge.

First claim

What is claimed is:

1. A thermal module for pre-heating liquid flowing into a liquid chromatography column, comprising:
a column compartment configured to hold a liquid chromatography column, the column compartment having a trough compartment with two ends, each of the ends having an electrical socket, the trough compartment having an elongated shape and a trough slidable within the trough compartment and configured to hold a liquid chromatography column and to cover an unused one of the electrical sockets; and
a pre-heater assembly plugged into an uncovered one of the electrical sockets, the pre-heater assembly including:
a heater block assembly including a heater block made of thermally conductive material, the heater block having a tube inlet, a tube outlet, and a tube path between the tube inlet and tube outlet;
tubing extending through the tube path from the tube inlet to the tube outlet, the tubing being in thermal communication with the heater block;
a heater cartridge in thermal communication with the heater block, the heater cartridge configured to provide heat to the heater block for transfer to liquid flowing through the tubing between the tube inlet and the tube outlet of the heater block assembly; and
circuitry in electrical communication with the heater cartridge to control a temperature of the heater block by controlling operation of the heater cartridge.

2. The thermal module of claim 1 , further comprising a column fitting configured to couple one end of the tubing that emerges from the tube outlet of the heater block assembly to an inlet port of a liquid chromatography column.

3. The thermal module of claim 1 , further comprising a tube fitting configured to couple an opposite end of the tubing that enters the tube inlet of the heater block assembly to an outlet port of a sample manager.

4. The thermal module of claim 1 , further comprising a temperature sensor in thermal communication with the heater block to provide an indication of the temperature of the heater block, and wherein the circuitry is in electrical communication with the temperature sensor to determine therefrom the temperature of the heater block.

5. The thermal module of claim 1 , wherein one end of the trough compartment has a groove for receiving the tubing.

6. The thermal module of claim 1 , wherein the circuitry includes a resistor used by external electronic circuitry to recognize a presence of the pre-heater assembly in the thermal module.

7. The thermal module of claim 1 , wherein the pre-heater assembly further comprises a leaf-spring carrier having a pair of opposing springy prongs, and wherein the heater block assembly is disposed between the prongs.

8. The thermal module of claim 7 , further comprising a receptacle configured to snap into each of the electrical sockets of the trough compartment and to receive the leaf-spring carrier.

Assignees

• Kirby Peter
• Lin Tony A
• Trudeau Steven D
• Waters Technologies Corp

Inventors

• Kirby Peter
• Lin Tony A
• Trudeau Steven D

Classifications

• G01N2030/3061

  column or associated structural member used as heater · CPC title

• G01N2030/3007

  same temperature for whole column · CPC title

• G01N30/54 Primary

  Temperature · CPC title

• G01N30/30 Primary

  of temperature · CPC title

• H05B3/42

  non-flexible · CPC title