Compositions and methods for viral sensitization
US-2024360115-A1 · Oct 31, 2024 · US
US9453005B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9453005-B2 |
| Application number | US-200913119052-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 21, 2009 |
| Priority date | Sep 16, 2008 |
| Publication date | Sep 27, 2016 |
| Grant date | Sep 27, 2016 |
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Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.
Opening claim text (preview).
What is claimed: 1. A method of treating an infection by influenza A virus comprising the step of administering to a subject in need thereof a composition comprising any of compounds 2-7, 10-12, and 14-27: or a stereoisomer, partial stereoisomer, pharmaceutically acceptable salt, or N-oxide thereof.
for influenza or rhinoviruses · CPC title
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
The ring being spiro-condensed with carbocyclic or heterocyclic ring systems · CPC title
only substituted in position 4 · CPC title
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
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