Inhibition of influenza M2 proton channel

US9453005B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9453005-B2
Application numberUS-200913119052-A
CountryUS
Kind codeB2
Filing dateAug 21, 2009
Priority dateSep 16, 2008
Publication dateSep 27, 2016
Grant dateSep 27, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.

First claim

Opening claim text (preview).

What is claimed: 1. A method of treating an infection by influenza A virus comprising the step of administering to a subject in need thereof a composition comprising any of compounds 2-7, 10-12, and 14-27: or a stereoisomer, partial stereoisomer, pharmaceutically acceptable salt, or N-oxide thereof.

Assignees

Inventors

Classifications

  • for influenza or rhinoviruses · CPC title

  • C07D409/06Primary

    linked by a carbon chain containing only aliphatic carbon atoms · CPC title

  • The ring being spiro-condensed with carbocyclic or heterocyclic ring systems · CPC title

  • only substituted in position 4 · CPC title

  • linked by a carbon chain containing only aliphatic carbon atoms · CPC title

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Frequently asked questions

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What does patent US9453005B2 cover?
Provided are compounds that are capable of modulating the activity of the influenza A virus via interaction with the M2 transmembrane protein. Also provided are methods for treating an influenza A-affected disease state or infection comprising administering a composition comprising one or more compounds that have been identified as being capable of interaction with the M2 protein.
Who is the assignee on this patent?
Degrado William F, Wang Jun, Univ Pennsylvania
What technology area does this patent fall under?
Primary CPC classification C07D409/06. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Sep 27 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).