Embolization device constructed from expansile polymer

Patent metadata

Field	Value
Publication number	US-9451963-B2
Application number	US-201213553275-A
Country	US
Kind code	B2
Filing date	Jul 19, 2012
Priority date	Jun 15, 2006
Publication date	Sep 27, 2016
Grant date	Sep 27, 2016

Abstract

Devices for the occlusion of body cavities, such as the embolization of vascular aneurysms and the like, and methods for making and using such devices. The devices may be comprised of novel expansile materials, novel infrastructure design, or both. The devices provided are very flexible and enable deployment with reduced or no damage to bodily tissues, conduits, cavities, etceteras.

First claim

We claim:

1. An implant delivery device comprising:
an occlusion device consisting essentially of:
an elongated expansile element composed substantially of expansile material comprising a poly(ethylene glycol) macromer; and
a microcoil comprising a plurality of loops forming a helical shape, wherein the loops are spaced by gaps, wherein at least one gap has a distance of about 0.00025 inches to about 0.2 inches helically disposed around said expansile element, wherein the at least one gap is dimensioned to allow the elongated expansile element to expand through the at least one gap and wherein the occlusion device has a bending resistance of about 0.1 mg to 25 mg.

2. The occlusion device of claim 1 , wherein said microcoil is between about 0.005 inches and about 0.035 inches in diameter.

3. The occlusion device of claim 1 , wherein said microcoil is about 0.012 inches in diameter.

4. The occlusion device of claim 3 , wherein said microcoil has a filar of about 0.002 inches.

5. The occlusion device of claim 4 , wherein the at least one gap has a distance of about 0.0013 inches.

6. The occlusion device of claim 1 , wherein said microcoil has a filar between about 0.0005 inches and about 0.01 inches.

7. The occlusion device of claim 1 , wherein said microcoil has a filar between about 0.00075 inches and about 0.004 inches.

8. The occlusion device of claim 1 , wherein said elongated expansile element is secured to said microcoil in a stretched configuration.

9. The occlusion device of claim 1 , wherein the at least one gap has a distance of about 0.00025 inches to about 0.005 inches.

10. The occlusion device of claim 1 , wherein the at least one gap has a distance of about 0.0013 inches.

11. The occlusion device of claim 1 , wherein said elongated expansile element is secured to said microcoil in a stretched configuration that is between about 125% and about 600% of its initial length.

12. The occlusion device of claim 1 , wherein said microcoil has a diameter of between about 0.008 inches and about 0.016 inches.

13. The occlusion device of claim 1 , wherein said microcoil has a filar of between about 0.0005 inches and about 0.01 inches.

14. The occlusion device of claim 13 , wherein said microcoil has a filar of between about 0.00075 inches and about 0.004 inches.

15. An implant delivery device comprising:
an occlusion device consisting essentially of:
an elongated expansile element composed substantially of expansile material comprising a poly(ethylene glycol) macromer; and
a carrier element comprising a plurality of loops forming a helical shape, wherein the loops are spaced by gaps, wherein at least one gap has a distance of about 0.00025 inches to about 0.2 inches helically disposed around said expansile element, wherein the at least one gap is dimensioned to allow the elongated expansile element to expand through the at least one gap and wherein the occlusion device has a bending resistance of about 0.1 mg to about 25 mg.

16. The occlusion device of claim 15 , wherein said carrier element has a diameter of about 0.012 inches and a filar of about 0.002 inches.

17. The occlusion device of claim 16 , wherein the at least one gap has a distance of about 0.0013 inches.

18. The occlusion device of claim 15 , wherein said carrier element has a diameter of between about 0.008 inches and about 0.016 inches.

19. The occlusion device of claim 15 , wherein said carrier element has a filar of between about 0.0005 inches and about 0.01 inches.

20. The occlusion device of claim 19 , wherein said carrier element has a filar of between about 0.00075 inches and about 0.004 inches.

21. The occlusion device of claim 15 , wherein said carrier element is between about 0.005 inches and about 0.035 inches in diameter.

22. The occlusion device of claim 21 , wherein said carrier element has a filar between about 0.0005 inches and about 0.01 inches.

23. The occlusion device of claim 22 , wherein the at least one gap has a distance of about 0.00025 inches to about 0.005 inches.

24. The occlusion device of claim 23 , wherein said elongated expansile element is secured to said carrier element in a stretched configuration that is between about 125% and about 600% of its initial length.

25. The occlusion device of claim 22 , wherein the at least one gap has a distance of about 0.0013 inches.

26. An implant delivery device comprising:
an occlusion device consisting essentially of:
a filament formed substantially of expansile material comprising a poly(ethylene glycol) macromer; and
a carrier element comprising a plurality of loops forming a helical shape, wherein the loops are spaced by gaps, wherein at least one gap has a distance of about 0.00025 inches to about 0.2 inches helically disposed around said filament, wherein the at least one gap is dimensioned to allow the elongated expansile element to expand through the at least one gap and wherein the occlusion device has a bending resistance of about 0.1 mg to about 25 mg.

27. The occlusion device of claim 26 , wherein said carrier element has a diameter of about 0.012 inches and a filar of about 0.002 inches.

28. The occlusion device of claim 27 , wherein the at least one gap has a distance of about 0.0013 inches.

29. The occlusion device of claim 26 , wherein said carrier element has a diameter of between about 0.008 inches and about 0.016 inches.

30. The occlusion device of claim 26 , wherein said carrier element has a filar of between about 0.0005 inches and about 0.01 inches.

31. The occlusion device of claim 30 , wherein said carrier element has a filar of between about 0.00075 inches and about 0.004 inches.

32. The occlusion device of claim 26 , wherein said carrier element is between about 0.005 inches and about 0.035 inches in diameter.

33. The occlusion device of claim 26 , wherein said carrier element has a filar between about 0.0005 inches and about 0.01 inches.

34. The occlusion device of claim 26 , wherein the at least one gap has a distance of about 0.00025 inches to about 0.005 inches.

35. The occlusion device of claim 26 , wherein said filament is secured to said carrier element in a stretched configuration that is between about 125% and about 600% of its initial length.

Assignees

• Cruise Gregory M
• Constant Michael
• Tran Terrance
• Gulachenski Joseph
• Microvention Inc

Inventors

• Cruise Gregory M
• Constant Michael
• Tran Terrance
• Gulachenski Joseph

Classifications

• A61L31/041

  Mixtures of macromolecular compounds · CPC title

• A61L31/06

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} · CPC title

• A61B17/12113 Primary

  within an aneurysm · CPC title

• A61L31/14

  Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} · CPC title

• A61B17/12154

  having stretch limiting means · CPC title