Cell analysis by mass cytometry

Patent metadata

Field	Value
Publication number	US-9435787-B2
Application number	US-201615001589-A
Country	US
Kind code	B2
Filing date	Jan 20, 2016
Priority date	Oct 26, 2012
Publication date	Sep 6, 2016
Grant date	Sep 6, 2016

Abstract

A combination of mutually exclusive cell-based analytical techniques can be applied to the same group of cells for analysis. The same group of cells can be prepared for analysis by each technique resulting with candidate cells targeted for mass cytometry analysis. This configuration allows for the correlation of the information between each technique to produce a matrix of multi dimension of cellular information with the same group of cells.

First claim

The invention claimed is:

1. A method for cellular analysis by mass cytometry comprising:
providing a group of cells labeled with more than one distinct elemental tag;
selecting a candidate cell in the group of cells by identifying a location at the candidate cell, the candidate cell having a property of interest;
recording the location at the candidate cell;
directing at least one laser pulse onto the candidate cell at the recorded location and generating a discrete plume f…

Assignees

• Fluidigm Canada Inc

Inventors

• Baranov Vladimir

Classifications

• G01N33/4833 Primary

  Physics · mapped topic

• G01N33/569

  Physics · mapped topic

• C12M1/343

  Chemistry & Metallurgy · mapped topic

• G01N2015/1006

  Physics · mapped topic

• G01N2001/045

  Physics · mapped topic