Self-contained system, apparatus and method for continuous isolation of extracellular vesicles.
US-2024003897-A1 · Jan 4, 2024 · US
US9435722B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9435722-B2 |
| Application number | US-201214353512-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 24, 2012 |
| Priority date | Oct 25, 2011 |
| Publication date | Sep 6, 2016 |
| Grant date | Sep 6, 2016 |
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A filter element and method for retaining particles of a medium, for example rare cells of blood. The filter element includes at least one opening that has an elongate cross section and/or a cross section that decreases in a flow direction. The filter element may be bordered by a transparent wall. The filter element may be provided with a plurality of elongate openings of a stepwise decreasing cross section that are arranged on a common transparent slide. The filter element permits high flow rates to be realized throughout the filtering process and the retained particles are immediately ready for visual inspection without a need for a further transfer.
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The invention claimed is: 1. A filter element for retaining components of a medium flowing in a flow direction through at least one opening, wherein said opening is a bottleneck in a flow path of the medium wherein the flow path is wider in front and behind the bottleneck; has an elongate cross section, measured perpendicular to the flow direction, that decreases along an extended length of the opening in the flow direction; and is bordered by a transparent wall.…
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