Composition and method for prevention, mitigation or treatment of an enteropathogenic bacterial infection
US-2015361045-A1 · Dec 17, 2015 · US
US9434687B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9434687-B2 |
| Application number | US-201213585646-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 14, 2012 |
| Priority date | Feb 14, 2011 |
| Publication date | Sep 6, 2016 |
| Grant date | Sep 6, 2016 |
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The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
Opening claim text (preview).
The invention claimed is: 1. An antibody that binds to structure: wherein R 4,1 is a C 4 or C 5 , substituted or unsubstituted, saturated or unsaturated, hydrocarbon chain; and, Y is substituted or unsubstituted naphthyl or substituted phenyl; and, wherein the antibody has a cross-reactivity presented as B/B 0 % of ≦15% (standardised with JWH-018 and using tracer ESC5913, wherein JWH-018 is wherein ESC5913 is and wherein HRP is Horse Radish Peroxidase) against each one of the cross-reactants selected from the group consisting of JWH-018, JWH-018 (N-(3-methylbutyl) isomer, JWH-073, JWH-073 4-methylnaphthyl analogue, JWH-022, JWH-081, JWH-081 5-methoxynaphthyl isomer, JWH-122, JWH-122 6-methylnaphthyl isomer, JWH-122 7-methylnaphthyl isomer, JWH-182, JWH-210, JWH-398, JWH-398 5-chloronaphthyl isomer, AM-694, AM-2201, and AM-2201 N-(4-fluoropentyl) isomer, at a cross-reactant concentration of 100 ng/ml, wherein B 0 is absorbance at 450 nm at zero ng/ml standard concentration, and wherein B is absorbance at 450 nm at predetermined standard concentrations.
Peptides being immobilised on, or in, an inorganic carrier · CPC title
Radicals substituted by oxygen atoms · CPC title
against material not provided for elsewhere {, e.g. haptens, metals, DNA, RNA, amino acids} · CPC title
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