Substituted pyridine and pyrimidine derivatives and their use in treating viral infections

US9433621B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9433621-B2
Application numberUS-201113579399-A
CountryUS
Kind codeB2
Filing dateFeb 18, 2011
Priority dateFeb 18, 2010
Publication dateSep 6, 2016
Grant dateSep 6, 2016

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  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R 1 , X, Y, Z, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 18 , R 19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.

First claim

Opening claim text (preview).

Therefore, We claim: 1. A compound, or a pharmaceutically acceptable salt thereof, selected from the group consisting of: Compd # Structure 2511 3137 3030 3182 3031 3188 3036 3239 3056 3438 3513 3569 3538 3580 3552 3721 3561 3744 3563 3754 3815A 4512 4025 4513 4346 4706

Assignees

Inventors

Classifications

  • for RNA viruses · CPC title

  • Ortho-condensed systems · CPC title

  • directly linked by a ring-member-to-ring-member bond · CPC title

  • A61K31/506Primary

    not condensed and containing further heterocyclic rings · CPC title

  • directly linked by a ring-member-to-ring-member bond · CPC title

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Frequently asked questions

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What does patent US9433621B2 cover?
The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R 1 , X, Y, Z, R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 18 , R 19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provide…
Who is the assignee on this patent?
Arasappan Ashok, Njoroge F George, Kwong Cecil D, and 20 more
What technology area does this patent fall under?
Primary CPC classification A61K31/506. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Sep 06 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).