Use of benzyloxy-ethylamine derivatives as a preservative, preservation method, and compositions

Patent metadata

Field	Value
Publication number	US-9427604-B2
Application number	US-201013512518-A
Country	US
Kind code	B2
Filing date	Nov 25, 2010
Priority date	Dec 11, 2009
Publication date	Aug 30, 2016
Grant date	Aug 30, 2016

Abstract

The invention relates to the use of a compound of formula (I), or salts thereof, as a preserving agent, in particular in a cosmetic, dermatological or pharmaceutical composition:

in which R1 and R2 represent H, methyl, ethyl, phenyl or benzyl.

The invention also relates to a method of preserving a cosmetic, dermatological or pharmaceutical composition, consisting in incorporating said compound of formula (I) therein; and also to the compositions thus obtained.

First claim

The invention claimed is:

1. A method for preserving a cosmetic, dermatological or pharmaceutical composition, which comprises incorporating into said composition as preserving agent at least one compound of formula (1) or a salt thereof

in which R1 is a hydrogen atom and R2 is a hydrogen atom or a benzyl radical.

2. A cosmetic, dermatological or pharmaceutical composition comprising, in a physiologically acceptable medium, at least one compound of formula (1), or a salt thereof:

in which R1 is a hydrogen atom and R2 is a hydrogen atom or a benzyl radical;
the compound of formula (1) and/or a salt thereof, alone or as a mixture, being present in an amount between 0.1 and 5% by weight, of the total weight of the composition.

3. The composition according to claim 2 , in which the at least one compound of formula (1) is salified and correspond to the formula (1′):

in which R1 is a hydrogen atom and R2 is a hydrogen atom or a benzyl radical; and X— is an organic and/or mineral, cosmetically acceptable anion, or mixture of anions.

4. The composition according to claim 2 , in which the compound of formula (1) or a salified form of (1) is chosen from:

5. The composition according to claim 2 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.25 and 3% by weight of the total weight of the composition.

6. The composition according to claim 2 , in which the physiologically acceptable medium comprises at least one ingredient chosen from: silicone fatty substances; non-silicone fatty substances; an aqueous medium; an aqueous-alcoholic medium containing a C 2 -C 6 monoalcohol; C 2 -C 6 alcohols, glycols; ketones; emulsifiers, surfactants, hydrophilic or lypophilic thickeners or gelling agents, and active agents.

7. The composition according to claim 2 , which is in the form of:
a product for making up the skin of the face, body or lips;
a sun protection composition or an artificial tanning composition;
an aftershave gel or lotion;
a hair-removing cream;
a body hygiene composition;
a pharmaceutical composition;
a solid composition;
an aerosol composition also comprising a pressurized propellent;
a hairsetting lotion, a hair-styling cream or gel, a dye composition; or
a composition for buccodental use.

8. The composition according to claim 5 , in which the compound of formula (1) or a salified form of (1) is chosen from:

9. The composition according to claim 3 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.25 and 3% by weight of the total weight of the composition.

10. The composition according to claim 4 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.25 and 3% by weight of the total weight of the composition.

11. The composition according to claim 2 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.5 and 2% by weight of the total weight of the composition.

12. The composition according to claim 6 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.25 and 3% by weight of the total weight of the composition.

13. The composition according to claim 7 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.25 and 3% by weight of the total weight of the composition.

14. The composition according to claim 3 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.5 and 2% by weight of the total weight of the composition.

15. The composition according to claim 4 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.5 and 2% by weight of the total weight of the composition.

16. The composition according to claim 6 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.5 and 2% by weight of the total weight of the composition.

17. The composition according to claim 7 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.5 and 2% by weight of the total weight of the composition.

18. The method according to claim 1 , in which the at least one compound of formula (1) is salified and correspond to the formula (1′):

in which R1 is a hydrogen atom and R2 is a hydrogen atom or a benzyl radical; and X— is an organic and/or mineral, cosmetically acceptable anion, or mixture of anions.

19. The method according to claim 1 , in which the compound of formula (1) or a salified form of (1) is chosen from:

20. The method according to claim 1 , in which the compound of formula (1) and/or a salt thereof, alone or as a mixture, is present in an amount between 0.25 and 3% by weight of the total weight of the composition.

Assignees

• Rozot Roger
• Dalko Maria
• Oreal

Inventors

• Rozot Roger
• Dalko Maria

Classifications

• A61Q5/00

  Preparations for care of the hair · CPC title

• A61P31/04

  Antibacterial agents · CPC title

• A61Q9/00

  Preparations for removing hair or for aiding hair removal · CPC title

• A61Q17/005 Primary

  Antimicrobial preparations · CPC title

• A61K2800/524

  Preservatives · CPC title