Medicated module for an inhaler

Patent metadata

Field	Value
Publication number	US-9427533-B2
Application number	US-201113988780-A
Country	US
Kind code	B2
Filing date	Nov 28, 2011
Priority date	Nov 29, 2010
Publication date	Aug 30, 2016
Grant date	Aug 30, 2016

Abstract

A medicated module containing a second medicament is configured for removable attachment to the mouthpiece of an inhaler containing a first medicament such that a single inhalation by a user will deliver both medicaments to the user.

First claim

The invention claimed is:

1. A medicated module configured for use with a drug inhaler containing a first medicament, the medicated module comprising:
a housing configured for attachment to the drug inhaler, where the housing has a distal end with a first opening and a proximal end with a second opening and a flow path extending between the first opening and the second opening;
a medicament container containing a dose of a second medicament; a seal attached to the housing to prevent the second medicament from entering the flow path;
a de-aggregation chamber configured to accept the second medicament from the medicament container upon opening the seal of the medicament container; and
a sliding member connected to the medicament container;
wherein the medicated module is configured such that attachment to the drug inhaler causes the sliding member to move in a distal direction such that the medicament container moves from a first position to a second position,
wherein the second position is closer to the second opening than the first position, and
wherein the movement of the container from the first position to the second position causes the seal to break, thereby opening the medicament container to the flow path, such that the first opening and the second opening are in fluid communication with the first medicament and the second medicament.

2. The medicated module of claim 1 where the medicament container and de-aggregation chamber are in fluid communication when the medicated module is in an attached state.

3. The medicated module of claim 1 where the medicament container is opened by the sliding member compressing the container against an inner portion of the housing.

4. The medicated module of claim 1 where the medicament container is a blister.

5. The medicated module of claim 1 where the de-aggregation chamber is in fluid communication with a mouthpiece of the drug inhaler when the medicated module is attached.

6. The medicated module of claim 1 wherein the de-aggregation chamber is in fluid communication with the flow path.

7. The medicated module of claim 1 wherein the first opening is configured as an outlet orifice, e.g. a mouthpiece of the module.

8. The medicated module of claim 1 wherein the second opening is configured to provide fluid communication between the flow path and the drug inhaler.

9. An inhaler drug delivery system comprising, in combination, the medicated module of claim 1 ; and a dry powder inhaler housing.

10. The inhaler drug delivery system according to claims 9 , wherein the dry powder inhaler housing further comprises a reservoir of the first medicament in the form of a powdered medicament.

Assignees

• Young Alasdair George
• De Sausmarez Lintell Daniel Thomas
• Mercer David Richard
• Sanofi Aventis Deutschland

Inventors

• Young Alasdair George
• De Sausmarez Lintell Daniel Thomas
• Mercer David Richard

Classifications

• A61M15/0031

  by bursting or breaking the package, i.e. without cutting or piercing · CPC title

• A61M15/0045

  using multiple prepacked dosages on a same carrier, e.g. blisters · CPC title

• A61M15/0021

  Mouthpieces therefor · CPC title

• A61M2202/064

  Powder · CPC title

• A61M31/00

  Devices for introducing or retaining media, e.g. remedies, in cavities of the body (A61M25/00 takes precedence {; introducing or retaining ophthalmic products into the ocular cavities A61F9/0008}) · CPC title