Tissue penetration device

Patent metadata

Field	Value
Publication number	US-9427532-B2
Application number	US-201414500497-A
Country	US
Kind code	B2
Filing date	Sep 29, 2014
Priority date	Jun 12, 2001
Publication date	Aug 30, 2016
Grant date	Aug 30, 2016

Abstract

An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft.

First claim

The invention claimed is:

1. A method of injecting an agent into the tissue of a patient at a known predetermined depth, comprising:
driving an elongate injection shaft using an electronic driver, the elongated injection shaft having an outlet port configured to dispense an agent at a controllable time toward the patient's target tissue;
providing programmable control of the electronic driver for a desired velocity of the injection shaft;
advancing the elongate injection shaft into the target tissue from the contact point over a displacement equal to the sum of an elastic recoil displacement value for the target tissue, the distance between a distal extremity of the elongate injection shaft and the outlet port, and the desired tissue depth of injection for agent deposition;
injecting the agent; and
accurately delivering the agent to a specific depth within a skin or tissue layer and provide for localized agent delivery; and further comprising: using a plurality of agent injection modules; and providing a series of metered doses of the agent.

2. The method of claim 1 , further comprising:
using a rapid insertion velocity to the specific depth to reduce pain of insertion of the needle into the skin.

3. The method of claim 1 , further comprising:
using a position feedback loop of the driver coupled to the elongate injection shaft.

4. The method of claim 1 , further comprising:
using an agent injection module that has a reservoir.

Assignees

• Sanofi Aventis Deutschland

Inventors

• Freeman Dominique M
• Alden Don

Classifications

• A61M5/2425

  by compression of deformable ampoule or carpule wall · CPC title

• A61M2005/005

  Magazines with multiple ampoules directly inserted into an injection or infusion device, e.g. revolver-like magazines containing ampoules with or without needles · CPC title

• A61M5/46 Primary

  having means for controlling depth of insertion · CPC title

• A61B5/1411

  by percutaneous method, e.g. by lancet · CPC title

• A61B5/442

  Evaluating skin mechanical properties, e.g. elasticity, hardness, texture, wrinkle assessment · CPC title