Gelatin sponge comprising an active ingredient, its preparation and use
US-8981058-B2 · Mar 17, 2015 · US
US9427490B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9427490-B2 |
| Application number | US-201514869311-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 29, 2015 |
| Priority date | Mar 3, 2008 |
| Publication date | Aug 30, 2016 |
| Grant date | Aug 30, 2016 |
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The present invention is directed to a method for manufacturing a cross-linked gelatin sponge having a surface by providing a cross-linked gelatin sponge, wetting the surface of the sponge by applying a sufficient amount of liquid comprising a protein or peptide active ingredient, wherein a sufficient amount of liquid is one that retains the flexibility of the sponge even after drying. The sponge is then dried the sponge to obtain a flexible, dry and ready to use cross linked gelatin sponge having a layer of protein or peptide active ingredient on the surface thereof.
Opening claim text (preview).
The invention claimed is: 1. A method for promoting blood coagulation, comprising administering to a wound or a bleeding site a cross-linked gelatin sponge obtained by the steps of: a) providing a cross-linked gelatin sponge having at least one surface; b) homogenously applying an aqueous liquid comprising a protein or peptide active ingredient to said at least one surface of said sponge, wherein the volume of the liquid intake into said surface of said sponge is equal to or les…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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