Apparatus and methods for accessing and sealing bodily vessels and cavities
US-2024415543-A1 · Dec 19, 2024 · US
US9427143B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9427143-B2 |
| Application number | US-52627108-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 10, 2008 |
| Priority date | Feb 8, 2007 |
| Publication date | Aug 30, 2016 |
| Grant date | Aug 30, 2016 |
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A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, adjacent chambers being fluidly connected, and a fluid source attached to one end of the set, such that the chambers inflate sequentially. The chambers are constructed of an elastic material and have a wall thickness and dimensions such that they have a characteristic with a non-monotonous relationship between the inflation pressure within the chamber and the chamber's inflated size. The characteristic is such that after an initial inflation pressure peak, the non-monotonous relationship adopts a negative slope, such that the volume of the chamber increases more rapidly than the volume of fluid flowing into it, and the inflation pressure of the chamber falls. This effect causes the chamber to inflate and anchor rapidly, while essentially slowing down the inflation of the succeeding chamber until inflation of the first is complete.
Opening claim text (preview).
We claim: 1. A method of generating self-propelled motion along a lumen, comprising: providing a set of serially arranged inflatable chambers, adjacent chambers being connected by at least one connecting port providing fluid communication between said adjacent chambers, at least one of said inflatable chambers having characteristics selected to provide, subsequent to its initial inflation and prior to its anchoring on a wall of said lumen, a non-monotonous relationship between the inflation pressure within said at least one chamber and its inflated size; inserting at least a portion of said set of serially arranged inflatable chambers into said lumen; and filling said set of serially arranged inflatable chambers through a fluid supply tube attached to an end chamber of said set of serially arranged inflatable chambers, wherein said at least one connecting port is configured to have predetermined fluid flow dynamics such that combination of said predetermined fluid flow dynamics and said characteristics causes the chambers of said set of serially arranged inflatable chambers to inflate sequentially, resulting in self-propelled motion along said lumen. 2. A method according to claim 1 and wherein said characteristics comprise the elastic properties of the material of said at least one chamber, the wall thickness of said at least one chamber, the uninflated size of said at least one chamber and the uninflated shape of said at least one chamber. 3. A method according to claim 1 , and wherein said characteristics are such that said non-monotonous relationship has an inflation pressure peak at a first inflated size. 4. A method according to claim 3 , and wherein said characteristics are such that said non-monotonous relationship has a negative slope when the inflated size of said at least one chamber is in a range immediately larger than said first inflated size. 5. A method according to claim 4 and wherein said characteristics are such that within said range immediately larger than said first inflated size, the volume of said at least one chamber increases more rapidly than the volume of fluid flowing into said at least one chamber, such that the inflation pressure of said at least one chamber falls. 6. A method according to claim 4 and wherein said characteristics are such that the slope of said non-monotonous relationship changes to a positive slope at a second inflated size within said range immediately larger than said first inflated size. 7. A method according to claim 6 and wherein said characteristics are such that at said second inflated size, said inflation pressure goes through a minimum as a function of inflated size. 8. A method according to claim 1 and wherein chambers in said set having equal inflation pressures can have different inflated sizes. 9. A method according to claim 1 and wherein said characteristics are such that said at least one inflatable chamber becomes fully inflated before a second chamber adjacent to said at least one inflatable chamber, and distal to said fluid supply tube, has inflated appreciably. 10. A method according to claim 9 and wherein said at least one inflatable chamber becomes fully inflated upon its anchoring to said wall of said lumen. 11. A method of generating self-propelled motion along a lumen, comprising: providing a set of serially arranged inflatable chambers, adjacent chambers being connected by at least one connecting port providing fluid communication between said adjacent chambers, at least one of said inflatable chambers having characteristics selected to provide, subsequent to its initial inflation and prior to its anchoring on a wall of said lumen, a non-monotonous relationship between the inflation pressure within said at least one chamber and its inflated size; inserting at least a portion of said set of serially arranged inflatable chambers into said lumen; and filling said set of serially arranged inflatable chambers through a fluid supply tube attached to an end chamber of said set of serially arranged inflatable chambers, wherein said at least one connecting port is configured to have predetermined fluid flow dynamics such that combination of said predetermined fluid flow dynamics and said characteristics causes the chambers of said set of serially arranged inflatable chambers to inflate one after another, resulting in self-propelled motion along said lumen.
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