Non-allergenic ingredients and food products

Patent metadata

Field	Value
Publication number	US-9427011-B2
Application number	US-36471709-A
Country	US
Kind code	B2
Filing date	Feb 3, 2009
Priority date	Aug 4, 2006
Publication date	Aug 30, 2016
Grant date	Aug 30, 2016

Abstract

The present invention relates to a non-allergenic food product, comprising an amino acid fraction comprising at least one component selected from the group consisting of amino acids and peptides having a degree of polymerization of 7 or less; and a lipid fraction comprising at least one fatty acid selected from the group consisting of arachidonic acid and docosahexanoic acid, the composition having a content of proteins and other peptides having a molecular weight of 1000 dalton or more of less than 0.01 wt. %, based on the dry weight, preferably less than 0.001 wt. %, more preferably less than 0.0001 wt %.

First claim

The invention claimed is:

1. A food product for ameliorating an allergic reaction in a subject by enterally administering the food product to the subject comprising:
an amino acid fraction comprising at least one component selected from the group consisting of amino acids and peptides having a degree of polymerization of 7 or less; and
a lipid fraction comprising at least one fatty acid selected from the group consisting of arachidonic acid and docosahexanoic acid,
wherein the food product having a content of proteins and other peptides having a molecular weight of 1000 dalton or more being less than 0.01 wt. %, based on the total dry weight of the product, and wherein the amino acid fraction further comprising less than 0.01 wt. % of proteins and other peptides having a degree of polymerization of 8 or more, based on the total dry weight of the product.

2. The food product according to claim 1 , further comprising a non-digestible carbohydrate fraction comprising at least 80 wt. %, based on the weight of the carbohydrate fraction, of oligosaccharides having a degree of polymerization in the range of 3-20, the oligomers comprising at least one or more moieties selected from the group consisting of fructose, galactose, glucuronic acid, galacturonic acids, xylose, mannose and arabinose moieties.

3. The food product according to claim 2 , with the oligosaccharides comprising at least two different monosaccharide units selected from the group consisting of galactose, fructose, uronic acids, xylose, arabinose and mannose.

4. The food product according to claim 3 , with the amino acid fraction comprising less than 0.001 wt. % of proteins and other peptides having a degree of polymerization of 8 or more.

5. The food product according to claim 2 , with the amino acid fraction comprising less than 0.001 wt. % of proteins and other peptides having a degree of polymerization of 8 or more.

6. The food product according to claim 1 , with at least 80 wt. % of the lipid fraction being provided by one or more lipids selected from the group consisting of triglycerides, diglycerides, mono-acylglycerides, phospholipids, lysophospholipids, ceramides, sphongosines, gangliosides, free fatty acids, salts of free fatty acids and esters of free fatty acids.

7. The food product according to claim 6 , with the amino acid fraction comprising less than 0.001 wt. % of proteins and other peptides having a degree of polymerization of 8 or more.

8. The food product according to claim 1 , with the amino acid fraction comprising less than 0.001 wt. % of proteins and other peptides having a degree of polymerization of 8 or more.

9. The food product according to claim 1 , with the amino acid fraction providing about 1.0-6.9 g arginine, about 5.5-12 g threonine and about 2.2-6.0 g tryptophan per 100 g amino acids.

10. The food product according to claim 9 , with the amino acid fraction comprising less than 0.001 wt. % of proteins and other peptides having a degree of polymerization of 8 or more.

11. The food product according to claim 1 , comprising at least one mineral selected from the group consisting of iron and copper.

12. The food product according to claim 1 , with the content of proteins and other peptides having a molecular weight of 1000 dalton or more being less than 0.001 wt. %.

13. The food product according to claim 1 , with the content of proteins and other peptides having a molecular weight of 1000 dalton or more being less than 0.0001 wt %.

14. The food product according to claim 1 , having a T-cell epitope content of less than 0.01 wt %.

15. The food product according to claim 1 , wherein the amino acid fraction comprises all essential amino acids.

16. The food product according to claim 1 , wherein the food product is intended for PKU patients and comprises all essential amino acids except for phenylalanine.

17. The food product according to claim 1 , wherein the amino acid fraction consists of amino acids.

Assignees

• Hageman Robert Johan Joseph
• Nutricia Nv

Inventors

• Hageman Robert Johan Joseph

Classifications

• A61P37/08

  Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14) · CPC title

• A61P1/12

  Antidiarrhoeals · CPC title

• A61P11/00

  Drugs for disorders of the respiratory system · CPC title

• A61P1/08

  for nausea, cinetosis or vertigo; Antiemetics · CPC title

• A61P11/06

  Antiasthmatics · CPC title