Modified carbocyanine dyes and their conjugates
US-2015247785-A1 · Sep 3, 2015 · US
Modified carbocyanine dyes and their conjugates
US9423323B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9423323-B2 |
| Application number | US-201514687584-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 15, 2015 |
| Priority date | Sep 29, 2000 |
| Publication date | Aug 23, 2016 |
| Grant date | Aug 23, 2016 |
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Abstract
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Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.
First claim
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What is claimed is: 1. A compound having a structure of the formula: wherein R 3 is -L-R x , L is C 6 alkyl, R x is a phosphoramidite, R 2 , R 4 and R 12 is methyl, and Z is O.
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linked by a chain containing hetero atoms as chain links · CPC title
four >CH- groups · CPC title
with fluorescent label · CPC title
Anthraquinone carboxylic acids · CPC title
linked by a carbon chain containing only aliphatic carbon atoms · CPC title
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- What does patent US9423323B2 cover?
- Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The inventio…
- Who is the assignee on this patent?
- Life Technologies Corp
- What technology area does this patent fall under?
- Primary CPC classification G01N1/30. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Aug 23 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).