Systems and methods for signal processing in molecular imaging
US-2024013454-A1 · Jan 11, 2024 · US
US9417334B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9417334-B2 |
| Application number | US-201414786223-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 22, 2014 |
| Priority date | Apr 25, 2013 |
| Publication date | Aug 16, 2016 |
| Grant date | Aug 16, 2016 |
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Preprocessing is conducted on a unipolar pulse output from a photomultiplier tube, to thereby generate a bipolar signal (bipolar pulse). In the bipolar signal, the falling waveform portion (back slope) of the initial peak waveform is steep, and also cuts across the baseline, whereby it is possible to accurately identify the falling point as the zero crossing point. The accuracy of identification of the pulse width “t” can be improved thereby. In addition to the pulse width, further reference may be made to the crest value of the unipolar pulse, the crest value of the bipolar signal, and the like, when determining line type.
Opening claim text (preview).
The invention claimed is: 1. A radiation measuring instrument, comprising: a detector configured to detect α-rays and β-rays and output a unipolar pulse; a preprocessing circuit configured to generate a bipolar pulse by applying waveform processing to the unipolar pulse output from the detector; a pulse width signal generating circuit configured to generate a pulse width signal representing a pulse width from a rising point to a falling point of the bipolar pulse; a large pulse detected signal generating circuit configured to generate a large pulse detected signal indicating that a crest value of the unipolar pulse is higher than a large pulse discrimination level, and a radiation type determining circuit configured to determine a radiation type of radiation from which the unipolar pulse is generated based at least on the pulse width signal and the large pulse detected signal. 2. The radiation measuring instrument according to claim 1 , wherein the bipolar pulse comprises a first portion protruding from the baseline toward one side and a second portion protruding from the baseline toward the other side, the second portion being continuous to the first portion, the rising point is a front end point of the first portion, and the falling point is a back end point of the first portion. 3. The radiation measuring instrument according to claim 2 , wherein the falling point is a cross point crossing the baseline. 4. The radiation measuring instrument according to claim 3 , wherein the pulse width signal generating circuit comprises: a reference signal generating circuit configured to generate a reference signal by smoothing the bipolar pulse; and a comparison circuit configured to compare the bipolar pulse with the reference signal to identify the rising point and the cross point. 5. The radiation measuring instrument according to claim 4 , wherein the pulse width signal generating circuit comprises an offset circuit configured to apply an offset to the bipolar pulse to thereby shift the bipolar pulse from a baseline represented by the reference signal, and the bipolar signal having the offset applied thereto is input to the comparison circuit. 6. The radiation measuring instrument according to claim 1 , wherein the unipolar pulse having a crest value exceeding the large pulse discrimination level is regarded as a pulse generated by α-ray detection. 7. The radiation measuring instrument according to claim 1 , further comprising: an effective pulse discrimination signal generating circuit configured to generate an effective pulse discrimination signal indicating that the bipolar pulse is an effective pulse having a crest value higher than a noise cut level and to output the effective pulse discrimination signal to the radiation type determining circuit, the noise cut level being a level for discriminating between noise and the effective pulse, the radiation type determining circuit determining the radiation type based at least on the pulse width signal, the large pulse detected signal, and the effective pulse discrimination signal. 8. The radiation measuring instrument according to claim 1 , further comprising: a high level discrimination signal generating circuit configure to generate a high level discrimination signal representing whether a crest value of the bipolar pulse is higher or lower than an intermediate level and to output the high level discrimination signal to the radiation type determining circuit, the intermediate level being a level for discriminating between a high crest value that can be generated by α-ray detection and β-ray detection and a low crest value that can be generated only by β-ray detection, the radiation type determining circuit determining the radiation type based at least on the pulse width signal, the large pulse detected signal, and the high level discrimination signal. 9. The radiation measuring instrument according to claim 1 , wherein the preprocessing circuit comprises a differentiating circuit and an integrating circuit. 10. The radiation measuring instrument according to claim 1 , wherein the detector comprises a single photomultiplier tube.
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