Optical measurement apparatus

Patent metadata

Field	Value
Publication number	US-9417235-B2
Application number	US-59307408-A
Country	US
Kind code	B2
Filing date	Nov 20, 2008
Priority date	Nov 20, 2008
Publication date	Aug 16, 2016
Grant date	Aug 16, 2016

Abstract

An object is to provide an optical measurement apparatus for performing an efficient test by optical measurement without incurring incorrect measurements.
To this end, the measurement apparatus utilizes a test instrument mounted thereto and including a carrier with a reagent retaining portion for application of a sample. The measurement apparatus includes a reader for color development at the reagent retaining portion, and a controller for driving control of the reader and for required determination. The controller performs the determination by utilizing the data obtained by reading the color development of the reagent after a reaction completion period Tr 1 -Tr 6 depending on the reagent and starting from the mounting of the test instrument. When detecting that the color development at the reagent retaining portion is completed before the lapse of the reaction completion period Tr 1 -Tr 6 after the mounting of the test instrument, the controller stops the test for the test instrument.

First claim

The invention claimed is:

1. An optical measurement apparatus comprising:
a test instrument including a carrier with a test reagent retaining portion, a confirmation reagent retaining portion, and said carrier capable of being applied with a sample for coloration reaction at the test reagent retaining portion and the confirmation reagent retaining portion;
a mount portion for mounting the test instrument;
a sensor for detecting the test instrument mounted at the mount portion;
a reader for optically reading color development at the test reagent retaining portion and the confirmation reagent retaining portion; and
a controller for performing driving control of the reader;
wherein the test instrument includes a test item code that is indicative of a reaction completion period set for the test instrument and stored in the controller as part of parameters,
wherein the reader is configured to read the test item code for the controller to set the reaction completion period,
wherein the controller is configured to perform test by utilizing data obtained by reading the color development at the test reagent retaining portion during and after the reaction completion period starting from the mounting of the test instrument at the mount portion,
wherein the controller is also configured to stop the test when the controller detects that the reading of the color development at the confirmation reagent retaining portion is higher than a first threshold value before lapse of the reaction completion period starting from the mounting of the test instrument at the mount portion, the first threshold value being set for the confirmation reagent retaining portion for storage in the controller as part of parameters, and
wherein the controller is further configured to continue the test by determining, immediately after the lapse of the reaction completion period, whether the reading of the color development at the test reagent retaining portion is higher than a second threshold value when the controller detects that the color development at the confirmation reagent retaining portion is not higher than the first threshold value before the lapse of the reaction completion period starting from the mounting of the test instrument, the second threshold value being set for the test reagent retaining portion for storage in the controller as part of the parameters and different from the first threshold value.

2. The optical measurement apparatus according to claim 1 , wherein the mount portion is configured to mount a plurality of test instruments.

3. The optical measurement apparatus according to claim 2 , wherein the plurality of test instruments are mounted in a row on the mount portion; and wherein the reader successively reads the plurality of test instruments in a direction in which the row extends.

4. The optical measurement apparatus according to claim 3 , wherein the reader is configured to perform the successive reading after the mounting of the test instruments and before the lapse of the reaction completion period.

5. The optical measurement apparatus according to claim 1 , wherein:
the test instrument is a test piece for immunochromatography;
the carrier comprises a porous film; and
the test reagent retaining portion contains an immunologic substance fixed to the porous film as the test reagent.

6. The optical measurement apparatus according to claim 1 , wherein:
the test instrument is a test strip to be dipped in a liquid;
the carrier comprises a porous film; and
the test reagent retaining portion contains an immunologic substance fixed to the porous film in a dry state as the test reagent.

7. The optical measurement apparatus according to claim 1 , wherein:
the test instrument is a test piece comprising the test reagent retaining portion to which the sample in liquid form is dropped;
the carrier comprises at least one of a high polymer compound and a porous film; and
a test reagent is fixed to at least one of the high polymer compound and the porous film in a dry state.

Assignees

• Nakagawa Takashi
• Nakajima Shinya
• Kasai Tokuo
• Ohshiro Kyouichi
• Arkray Inc

Inventors

• Nakagawa Takashi
• Nakajima Shinya
• Kasai Tokuo
• Ohshiro Kyouichi

Classifications

• G01N21/8483 Primary

  Investigating reagent band (test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04) · CPC title

• G01N33/52

  Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper {and including single- and multilayer analytical elements (immunological elements G01N33/54386; involving labelled immunochemicals G01N33/58; for haemoglobin or occult blood G01N33/72)} · CPC title

• G01N33/54386 Primary

  Analytical elements · CPC title

• Y10T436/11

  Automated chemical analysis · CPC title

• Y10T436/12

  Condition responsive control · CPC title