Compost system with error detection
US-2015368605-A1 · Dec 24, 2015 · US
Apparatus and methods for manipulation and optimization of biological systems
US9416429B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9416429-B2 |
| Application number | US-201414281664-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 19, 2014 |
| Priority date | Nov 18, 2004 |
| Publication date | Aug 16, 2016 |
| Grant date | Aug 16, 2016 |
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Abstract
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A method for optimization of a response of a biological system includes: (1) obtaining measurements of a biological system in response to varying concentrations of drugs in a drug combination; (2) fitting the measurements into a model of the biological system; and (3) using the model of the biological system, predicting concentrations of the drugs in the drug combination to yield an optimized response of the biological system.
First claim
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What is claimed is: 1. A method for optimization of a response of a biological system, comprising: obtaining measurements of a biological system in response to varying concentrations of drugs in a drug combination; fitting the measurements into a model of the biological system; and predicting concentrations of the drugs in the drug combination to yield an optimized response of the biological system, based on a predicted response of the biological system according to the model. 2. The method of claim 1 , wherein fitting the measurements includes determining multiple fitting parameters of the model. 3. The method of claim 2 , further comprising: determining predicted responses of the biological system to varying concentrations of the drugs; obtaining measured responses of the biological system to the varying concentrations of the drugs; and determining one or more of the fitting parameters by reducing deviations between the predicted responses and the measured responses. 4. The method of claim 1 , further comprising: determining optimized concentrations of the drugs based on the model; and directing the optimized concentrations of the drugs to be applied to the biological system. 5. The method of claim 1 , further comprising: selecting a drug to be applied to the biological system based on the model. 6. The method of claim 1 , further comprising: determining a predicted response time of the biological system, based on the model.
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Classifications
optimisation; experiment design · CPC title
- C12Q3/00Primary
Condition responsive control processes (apparatus therefor C12M1/36; controlling or regulating in general G05) · CPC title
- C12Q1/02Primary
involving viable microorganisms · CPC title
Automatic or computerized control (automatic analysis G01N35/00) · CPC title
- G01N35/0092Primary
Scheduling · CPC title
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- What does patent US9416429B2 cover?
- A method for optimization of a response of a biological system includes: (1) obtaining measurements of a biological system in response to varying concentrations of drugs in a drug combination; (2) fitting the measurements into a model of the biological system; and (3) using the model of the biological system, predicting concentrations of the drugs in the drug combination to yield an optimized r…
- Who is the assignee on this patent?
- Univ California
- What technology area does this patent fall under?
- Primary CPC classification C12Q3/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Aug 16 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).