Pyridyl aminopyridines as Syk inhibitors
US-9120785-B2 · Sep 1, 2015 · US
US9416111B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9416111-B2 |
| Application number | US-201314409200-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 17, 2013 |
| Priority date | Jun 22, 2012 |
| Publication date | Aug 16, 2016 |
| Grant date | Aug 16, 2016 |
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The invention provides certain substituted diazine and triazine compounds of the Formula (I) (I) or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 3 , R 4 , R cy , C y , and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
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What is claimed is: 1. A compound of the Formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1 is selected from the group consisting of H, C 1 -C 3 alkyl, C 1 -C 3 fluoroalkyl, C 1 -C 3 alkoxy, and C 3 -C 6 cycloalkyl; R 2 is selected from the group consisting of H, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, C 1 -C 3 fluoroalkyl, halo, and cyano; R 3…
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