Method for decreasing inflammation and stress in a mammal

Patent metadata

Field	Value
Publication number	US-9415083-B2
Application number	US-1231708-A
Country	US
Kind code	B2
Filing date	Feb 1, 2008
Priority date	May 10, 2004
Publication date	Aug 16, 2016
Grant date	Aug 16, 2016

Abstract

A method for decreasing inflammation and stress in a mammal comprising; administration to a mammal a composition comprising a glucose anti-metabolite; and wherein said composition comprises amounts of the glucose anti-metabolite sufficient to lower a level of a C-reactive protein in the blood of the mammal subsequent to administration of the glucose anti-metabolite.

First claim

What is claimed:

1. A method for decreasing inflammation and stress in a mammal comprising: administration to a mammal a composition comprising avocado fruit; and wherein said composition comprises amounts of the avocado fruit sufficient to lower a level of a C-reactive protein in the blood of the mammal subsequent to administration of the avocado;
wherein administration is daily and the dose of avocado fruit is about 100 mg/kg to about 200 g/kg; and wherein the composition comprises less than 5% of said avocado fruit, by weight of the composition.

2. The method of claim 1 , wherein the level of said C-reactive protein in the blood subsequent to administration of the avocado is from about 0 mg/L to about 100 mg/L.

3. The method of claim 1 , wherein the administration is oral.

4. The method of claim 1 , wherein said composition is selected from the group consisting of pet food, dog food, cat food, treats, chew, biscuits, gravy, sauce, beverage, supplemental water, and combinations thereof.

5. The method of claim 4 , wherein the composition is a nutritionally balanced pet food composition.

6. The method of claim 1 , further comprising animal protein, plant protein, farinaceous matter, vegetables, fruit, egg-based materials, undenatured proteins, food grade polymeric adhesives, gels, polyols, starches, gums, flavorants, seasonings, salts, colorants, time-release compounds, minerals, vitamins, antioxidants, prebiotics, probiotics, aroma modifiers, lipids, and combinations thereof.

7. The method of claim 1 , wherein the level of said C-reactive protein in the blood subsequent to administration of the avocado is from about 0 mg/L to about 100 mg/L.

8. A method for decreasing inflammation and stress in a mammal comprising: administration to a mammal a composition comprising mannoheptulose; and wherein said composition comprises amounts of the mannoheptulose sufficient to lower the level of a C-reactive protein in the blood of the mammal subsequent to administration of the mannoheptulose;
wherein administration is daily and the dose of mannoheptulose is about 2 mg/kg to about 5 mg/kg; and wherein the composition comprises less than 5% of said mannoheptulose, by weight of the composition.

9. The method of claim 8 , wherein the level of said C-reactive protein in the blood subsequent to administration of the mannoheptulose is from about 0 mg/L to about 100 mg/L.

10. The method of claim 8 , wherein the level of said C-reactive protein in the blood subsequent to administration of the mannoheptulose is from about 0.1 mg/L to about 60 mg/L.

11. The method of claim 8 , wherein the level of said C-reactive protein in the blood subsequent to administration of the mannoheptulose is from about 0.2 mg/L to about 40 mg/L.

12. The method of claim 8 , wherein said mannoheptulose is selected from the group consisting of avocado extract, avocado, and combinations thereof.

13. The method of claim 8 , wherein the administration is oral.

14. The method of claim 8 , wherein said composition is selected from the group consisting of pet food, dog food, cat food, treats, chew, biscuits, gravy, sauce, beverage, supplemental water, and combinations thereof.

15. The method of claim 8 , wherein the composition is a nutritionally balanced pet food composition.

16. The method of claim 8 , further comprising animal protein, plant protein, farinaceous matter, vegetables, fruit, egg-based materials, undenatured proteins, food grade polymeric adhesives, gels, polyols, starches, gums, flavorants, seasonings, salts, colorants, time-release compounds, minerals, vitamins, antioxidants, prebiotics, probiotics, aroma modifiers, lipids, and combinations thereof.

17. A method for decreasing inflammation and stress in a mammal comprising: administration to a mammal a composition comprising avocado extract; and wherein said composition comprises amounts of the avocado extract sufficient to lower the level of a C-reactive protein in the blood of the mammal subsequent to administration of the avocado extract;
wherein administration is daily and the avocado extract comprises a dose of glucose anti-metabolite at about 2 mg/kg to about 5 mg/kg; and wherein the composition comprises less than 5% of said avocado extract, by weight of the composition.

18. The method of claim 17 , wherein the level of said C-reactive protein in the blood subsequent to administration of the avocado extract is from about 0 mg/L to about 100 mg/L.

19. The method of claim 17 , wherein the level of said C-reactive protein in the blood subsequent to administration of the avocado extract is from about 0.1 mg/L to about 60 mg/L.

20. The method of claim 17 , wherein the level of said C-reactive protein in the blood subsequent to administration of the avocado extract is from about 0.2 mg/L to about 40 mg/L.

21. The method of claim 17 , wherein the administration is oral.

22. The method of claim 17 , wherein said composition is selected from the group consisting of pet food, dog food, cat food, treats, chew, biscuits, gravy, sauce, beverage, supplemental water, and combinations thereof.

23. The method of claim 17 , wherein the composition is a nutritionally balanced pet food composition.

24. The method of claim 17 further comprising animal protein, plant protein, farinaceous matter, vegetables, fruit, egg-based materials, undenatured proteins, food grade polymeric adhesives, gels, polyols, starches, gums, flavorants, seasonings, salts, colorants, time-release compounds, minerals, vitamins, antioxidants, prebiotics, probiotics, aroma modifiers, lipids, and combinations thereof.

Assignees

• Massimino Stefan Patrick
• Davenport Gary Mitchell
• Hayek Michael Griffin
• Roth George
• Ingram Donald K
• Mars Inc

Inventors

• Massimino Stefan Patrick
• Davenport Gary Mitchell
• Hayek Michael Griffin
• Roth George
• Ingram Donald K

Classifications

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P25/20

  Hypnotics; Sedatives · CPC title

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61P25/00

  Drugs for disorders of the nervous system · CPC title

• A61K31/70

  Carbohydrates; Sugars; Derivatives thereof (sorbitol A61K31/047) · CPC title