Vascular closure device with biodegradable anchor

Patent metadata

Field	Value
Publication number	US-9414821-B2
Application number	US-84189510-A
Country	US
Kind code	B2
Filing date	Jul 22, 2010
Priority date	Jul 22, 2010
Publication date	Aug 16, 2016
Grant date	Aug 16, 2016

Abstract

This disclosure pertains to controllably bioabsorbable devices, particularly anchors for vascular closure plugs and to methods of use thereof.

First claim

What is claimed is:

1. A bioabsorbable anchor for a vascular closure device comprising:
a magnesium anchor;
a biodegradable polymer coating associated with the magnesium anchor;
a conductive element connected to the magnesium anchor; and
a biodegradable electroactive polymer associated with one or more of the magnesium anchor, the biodegradable polymer, and the conductive element.

2. The bioabsorbable anchor of claim 1 , wherein the biodegradable electroactive polymer includes poly(3,4-ethylenedioxythiophene).

3. The bioabsorbable anchor of claim 1 , wherein the biodegradable polymer coating includes at least one of polylactic acid, polyglycolic acid, or a combination of polylactic acid and polyglycolic acid.

4. The bioabsorbable anchor of claim 1 , wherein the biodegradable polymer coating further comprises a heteropolyacid.

5. The bioabsorbable anchor of claim 1 , wherein the magnesium anchor comprises magnesium foam.

6. The bioabsorbable anchor of claim 5 , wherein the magnesium foam further comprises a heteropolyacid.

7. The bioabsorbable anchor of claim 1 , wherein the magnesium anchor is coated with at least one of polylactic acid, polyglycolic acid, or a combination of polylactic acid and polyglycolic acid.

8. The bioabsorbable anchor of claim 7 , wherein the coated magnesium anchor is further coated with a heteropolyacid.

9. The bioabsorbable anchor of claim 1 , wherein the conductive element connected to the magnesium anchor is coated with a biodegradable polymer.

10. The bioabsorbable anchor of claim 1 , wherein the magnesium anchor is connected to a source of electric current.

11. A method of deploying a vascular closure device comprising:
providing an anchor for a vascular closure device, said anchor further comprising:
a magnesium anchor member;
a biodegradable polymer coating associated with the magnesium anchor member;
a conductive element connected to the magnesium anchor member; and
a biodegradable electroactive polymer associated with one or more of the magnesium anchor, the biodegradable polymer, and the conductive element;
disposing the anchor in a blood vessel such that the conductive element extends through a puncture site in a wall of the blood vessel;
applying tension to the conductive element to seat the anchor against a vessel wall at the puncture site;
positioning a biodegradable hemostatic plug adjacent to an exterior vessel wall opposite the anchor; and
passing an electric current through the magnesium anchor member via the conductive element connected to the magnesium anchor member thereby causing the anchor to dissolve at a rate different from the rate at which the anchor would dissolve in the absence of the electric current.

12. The method of claim 11 , wherein the biodegradable hemostatic plug comprises a biodegradable electroactive polymer.

13. The method of claim 11 , wherein at least one of the biodegradable hemostatic plug, the magnesium anchor member, and the biodegradable polymer coating the magnesium anchor member includes poly(3,4-ethylenedioxythiophene).

14. The method of claim 11 , wherein the electric current is supplied from a source outside of a body.

15. The method of claim 11 , wherein the electric current is supplied from a source inside of a body.

16. The method of claim 11 , wherein the anchor further comprises a heteropolyacid.

17. The method of claim 11 , wherein the magnesium anchor member comprises a magnesium foam.

18. A bioabsorbable anchor for vascular closure devices comprising:
a magnesium anchor;
a biodegradable polymer coating the magnesium anchor;
a biodegradable electroactive polymer;
a heteropolyacid;
a conductive element connected to the magnesium anchor; and
a source of electric current connected to the magnesium anchor by the conductive element.

19. The bioabsorbable anchor of claim 18 , wherein the magnesium anchor comprises magnesium foam.

20. The bioabsorbable anchor of claim 18 , wherein the heteropolyacid is present in at least one of the magnesium anchor, the biodegradable polymer coating, the biodegradable electroactive polymer, and combinations thereof.

Assignees

• Atanasoska Liliana
• Sogard David J
• Warner Robert W
• Root Michael
• Radhakrishnan Rajesh
• Rahi Mourad
• Smith Scott R
• Weber Jan
• Petersen Eric
• Boston Scient Scimed Inc

Inventors

• Atanasoska Liliana
• Sogard David J
• Warner Robert W
• Root Michael
• Radhakrishnan Rajesh
• Rahi Mourad
• Smith Scott R
• Weber Jan
• Petersen Eric

Classifications

• A61B2017/00411

  actuated by application of energy from an energy source outside the body · CPC title

• A61B17/0057 Primary

  Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009) · CPC title

• A61B2017/00654

  entirely comprised between the two sides of the opening · CPC title

• A61B2017/00004

  (bio)absorbable, (bio)resorbable or resorptive · CPC title

• A61B2017/00659

  located only on one side of the opening · CPC title