Blood pressure estimation method and biological information measurement system
US-2024423547-A1 · Dec 26, 2024 · US
US9414773B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9414773-B2 |
| Application number | US-201214125182-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 19, 2012 |
| Priority date | Jun 21, 2011 |
| Publication date | Aug 16, 2016 |
| Grant date | Aug 16, 2016 |
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A respiratory motion determination apparatus determines respiratory motion of a living being ( 3 ). A raw data providing unit ( 2 ) provides raw data assigned to different times, wherein the raw data are indicative of a structure like the apex of the heart muscle, which is influenced by cardiac motion and by respiratory motion. A reconstruction unit ( 6 ) reconstructs intermediate images of the structure from the provided raw data. A structure detection unit ( 7 ) detects the structure in the reconstructed intermediate images. A respiratory motion determination unit ( 10 ) determines the respiratory motion of the living being based on the structure detected in the reconstructed intermediate images. This allows determining respiratory motion with high accuracy, without relying on, for example, a stable correlation between a tracking signal of an external respiratory gating device and respiratory phases.
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The invention claimed is: 1. A respiratory motion determination apparatus for determining respiratory motion of a living being, the respiratory motion determination apparatus comprising: a raw data providing unit for providing raw data assigned to different times, wherein the raw data are indicative of a structure, which is influenced by cardiac motion and by respiratory motion of the living being and which is a structure of the living being, wherein the raw data are usable for reconstructing an image of the structure, a reconstruction unit for reconstructing intermediate images of the structure from the provided raw data, a structure detection unit for detecting the structure in the reconstructed intermediate images, a respiratory motion determination unit for determining the respiratory motion of the living being based on the structure detected in the reconstructed intermediate images, wherein the raw data providing unit is adapted to provide nuclear raw data as the raw data and the respiratory motion determination unit is adapted to determine the positions of the structure in the reconstructed intermediate images as the respiratory motion of the living being and to determine for each reconstructed intermediate image the respective respiratory phase of the living being depending on the positions of the structure detected in the reconstructed intermediate images. 2. The respiratory motion determination apparatus as defined in claim 1 , further comprising: a cardiac signal providing unit for providing a cardiac signal at the different times to which the raw data are assigned, wherein the cardiac signal is indicative of heart cycles, a raw data grouping unit for grouping raw data of a same heart cycle in a group based on the provided cardiac signal, wherein the reconstruction unit is adapted to reconstruct an intermediate image for each group depending on the raw data of the respective group. 3. The respiratory motion determination apparatus as defined in claim 1 , wherein the structure detection unit is adapted to detect the apex of the heart muscle as the structure. 4. The respiratory motion determination apparatus as defined in claim 1 , further comprising: a respiratory phase image set providing unit for providing a respiratory phase image set of the living being, wherein the respiratory phase image set comprises for different respiratory phases different images of the structure, wherein the respiratory motion determination unit is adapted to determine the respiratory phase of a reconstructed intermediate image by comparing the position of the structure in the reconstructed intermediate image with the position of the structure in the respiratory phase image set. 5. The respiratory motion determination apparatus as defined in claim 1 , further comprising: a respiratory motion model providing unit for providing a respiratory motion model of the living being, wherein the respiratory motion model provides for different respiratory phases different positions of the structure, wherein the respiratory motion determination unit is adapted to determine the respiratory phase of a reconstructed intermediate image by comparing the position of the structure in the reconstructed intermediate image with the position of the structure in the respiratory motion model. 6. The respiratory motion determination apparatus as defined in claim 1 , wherein the respiratory motion determination unit is adapted to fit a trajectory to the respiratory movement of the structure and to determine respiratory phases based on the fitted trajectory, thereby defining respiratory phases for the reconstructed intermediate images. 7. The respiratory motion determination apparatus as defined in claim 1 , wherein the reconstruction unit is adapted to reconstruct for different respiratory phases different respiratory phase images based on the raw data of the respective respiratory phase. 8. The respiratory motion determination apparatus as defined in claim 7 , wherein the raw data are nuclear raw data and wherein the reconstructed intermediate images are reconstructed nuclear images, wherein the respiratory motion determination apparatus further comprises a respiratory phase image set providing unit for providing a respiratory phase image set of the living being, wherein the respiratory phase image set comprises for different respiratory phases different attenuation images of the living being, wherein the reconstruction unit is further adapted to attenuation-correct the different nuclear respiratory phase images based on the determined respiratory phases and the provided respiratory phase image set. 9. A respiratory motion determination apparatus for determining respiratory motion of a living being, the respiratory motion determination apparatus comprising: a raw data providing unit for providing raw nuclear data assigned to different times, wherein the raw nuclear data are indicative of a structure, which is influenced by cardiac motion and by respiratory motion of the living being and which is a structure of the living being, wherein the raw data are usable for reconstructing an image of the structure; a reconstruction unit for reconstructing intermediate nuclear images of the structure from the provided raw data; a structure detection unit for detecting the structure in the reconstructed intermediate images; a respiratory motion determination unit for determining the respiratory motion of the living being based on the structure detected in the reconstructed intermediate images; wherein the respiratory motion determination apparatus further comprises: a respiratory motion model providing unit for providing a respiratory motion model of the living being, wherein the respiratory motion model provides for different respiratory phases different positions of the structure, and a static attenuation image providing unit for providing a static attenuation image, wherein the reconstruction unit is adapted to: deform the static attenuation image in accordance with the provided respiratory motion model for producing different attenuation images for different respiratory phases, attenuation-correct each reconstructed intermediate image based on the attenuation image produced for the respiratory phase of the respective reconstructed intermediate nuclear image. 10. The respiratory motion determination apparatus as defined in claim 1 , wherein the reconstruction unit is adapted to register the different respiratory phase images and to average the registered respiratory phase images for producing a static image. 11. The respiratory motion determination apparatus as defined in claim 1 , wherein the reconstruction unit is adapted to reconstruct a respiratory motion compensated image from the raw data and the determined respiratory motion. 12. A respiratory motion determination method for determining respiratory motion of a living being, the respiratory motion determination method comprising: providing nuclear raw data assigned to different times from a nuclear imaging system, wherein the raw nuclear data are indicative of a structure of the living being, which is influenced by cardiac motion and by respiratory motion of the living being and which is a structure of the living being, wherein the nuclear raw data are usable for reconstructing an image of the structure, reconstructing non-attenuation corrected intermediate nuclear images of the structure from the provided nuclear raw data with a computer system, detecting positions in the structure in the reconstructed non-attenuated corrected intermediate nuclear images, with the computer system, determining a respiratory phase of the living being in each reconstructe
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