Nanoparticle probes, methods, and systems for use thereof

Patent metadata

Field	Value
Publication number	US-9410934-B2
Application number	US-201214350908-A
Country	US
Kind code	B2
Filing date	Jul 5, 2012
Priority date	Oct 20, 2011
Publication date	Aug 9, 2016
Grant date	Aug 9, 2016

Abstract

Methods of identifying geological materials of interest comprising (i) providing a nanoprobe composition comprising one or more nanoprobes; wherein the nanoprobe includes (a) at least one tag; and (b) at least one signal generator; (ii) introducing the nanoprobes to a geological material; and (iii) detecting the presence of a signal generated by the signal generator on association of the tag with a target. Nanoprobe compositions identify geological materials, systems include such nanoprobe compositions, and methods use such nanoprobe compositions for the evaluation of geological materials.

First claim

What is claimed is:

1. A method of identifying geological materials of interest comprising:
(i) providing a nanoprobe composition comprising one or more nanoprobes;
wherein the nanoprobe comprises:
(a) at least one tag; and
(b) at least one signal generator;

(ii) introducing the nanoprobes to a geological material; and
(iii) detecting the presence of a signal generated by the signal generator on association of the tag with a target.

2. The method of claim 1 , wherein introducing the nanoprobes to the geological material occurs ex situ or in situ.

3. The method of claim 2 , wherein the ex situ introduction of the nanoprobes to the geological material comprises contacting the nanoprobes with a sample.

4. The method of claim 1 , wherein the in situ introduction of the nanoprobes to a geological material comprises injecting the nanoprobes into a subsurface formation or contacting the nanoprobes with a seep.

5. The method of claim 1 , wherein the target is at least one of hydrocarbons, microorganisms that metabolize the geological material, and compounds produced by the microorganisms that metabolize the geological material.

6. The method of claim 1 , wherein the target is one of genetic material of microorganisms that metabolize the geological material, polysaccharides found on the cell walls of microorganisms that metabolize the geological material, and proteins or sterols found in the cell membranes of microorganisms that metabolize the geological material.

7. The method of claim 1 , wherein the tag is one or more of a hydrocarbon, a DNA, and a RNA tracer.

8. The method of claim 1 , wherein the signal generator is a nanoparticle.

9. The method of claim 1 , wherein the signal generator is an inorganic fluorophore.

10. The method of claim 8 , wherein the nanoparticle is one or more of a silicon nanoparticle, a cadmium selenide nanoparticle, a cadmium-sulfide nanoparticle, a quantum dot, a nanoparticle composite, a nanocrystal, and a carbon nanotube.

11. The method of claim 1 , wherein association of the tag with the target comprises one or more of sorbing, partitioning, anionic bonding, hydrogen bonding, covalent bonding, and adhesion.

12. The method of claim 1 , wherein the signal generated is at least one of an audible, a sonar, an acoustic, a visible, and a fluorescent signal.

13. The method of claim 1 , wherein the tag is a DNA or RNA primer and the target is genetic material of the microorganisms that metabolize the geological material.

14. The method of claim 1 , wherein detecting further comprises using one or more of a UV-Vis spectrometer, IR spectrometer, a fluorimeter, a Raman spectrometer, and a sonar detector.

15. A nanoprobe composition comprising:
one or more nanoprobes, wherein the nanoprobe comprises:
(a) at least one tag capable of associating with a target found in geological materials; and
(b) at least one signal generator capable of generating a signal when the tag associates with the target.

16. The nanoprobe composition of claim 15 , further comprising a reagent.

17. The nanoprobe composition of claim 16 , wherein the reagent is selected from the group consisting of drilling fluids, water, brine, organic solvents, and a mixture thereof.

18. The nanoprobe composition of claim 15 , wherein the tag is one or more of a hydrocarbon, a DNA, and a RNA tracer.

19. The nanoprobe composition of claim 15 , wherein the signal generator is a nanoparticle.

20. The nanoprobe composition of claim 15 , wherein the signal generator is an inorganic fluorophore.

21. The nanoprobe composition of claim 18 , wherein the nanoparticle is one or more of a silicon nanoparticle, a cadmium selenide nanoparticle, a cadmium-sulfide nanoparticle, a quantum dot, a nanoparticle composite, a nanocrystal, and a carbon nanotube.

22. The nanoprobe composition of claim 15 , wherein the signal generated is at least one of an audible, a sonar, an acoustic, a visible, and a fluorescent signal.

23. An article comprising the nanoprobe composition of claim 15 .

24. The article of claim 23 , wherein the article is at least one of a sheet, film, net, or mesh.

25. A method of evaluating a geological material comprising:
(a) providing a first nanoprobe;
wherein the first nanoprobe comprises:
(i) one or more tags that associate with a target; and
(ii) one or more first signal generators;

(b) providing a second nanoprobe;
wherein the second nanoprobe comprises:
(i) one or more tags that associate with water; and
(ii) one or more second signal generators;

(c) introducing a nanoprobe composition comprising the first nanoprobe and the second nanoprobe to the geological materials;
(d) measuring the first signal;
wherein the first signal is generated upon the association of the first nanoprobe with the target;
(e) measuring the second signal;
wherein the second signal is generated upon the association of the second nanoprobe with water;
(f) comparing the first signal to the second signal; and
(g) deriving an estimation of the respective proportions of water and target in the geological materials.

26. The method of claim 25 , wherein the tag of the second nanoprobe is hydrophilic.

27. The method of claim 25 , wherein the tag of the first nanoprobe is hydrophobic.

28. The method of claim 25 , wherein the first and/or second signal generated is at least one of an audible, a sonar, an acoustic, a visible, and a fluorescent signal.

29. The method of claim 25 , wherein the nanoprobe composition further comprises a reagent.

30. The method of claim 25 , wherein the reagent is selected from the group consisting of drilling fluids, water, brine, organic solvents, and a mixture thereof.

31. A system for the characterization of geological materials comprising:
(a) a nanoprobe composition comprising one or more nanoprobes;
wherein the nanoprobe comprises:
(i) at least one tag; and
(ii) at least one signal generator; and

(b) at least one detector capable of detecting a signal generated by the signal generator.

32. The system of claim 31 , further comprising a means for introducing the nanoprobe composition downhole.

33. The system of claim 31 , wherein the nanoprobe composition further comprises a reagent.

34. The system of claim 33 , wherein the reagent is selected from the group consisting of drilling fluids, water, brine, organic solvents, and a mixture thereof.

35. The system of claim 31 , wherein the nanoprobe composition is provided in the form of a sheet, film, net, or mesh.

Assignees

• Robinson Amelia C
• Pottorf Robert J
• Jones Daniel S
• Dreyfus Sebastien L
• Exxonmobil Upstream Res Co

Inventors

• Robinson Amelia C
• Pottorf Robert J
• Jones Daniel S
• Dreyfus Sebastien L

Classifications

• G01N21/78

  producing a change of colour · CPC title

• G01N33/241 Primary

  for hydrocarbon content · CPC title

• G01N33/24

  Earth materials (G01N33/42 takes precedence) · CPC title

• G01N2021/6432

  Quenching · CPC title

• G01V9/007

  by detecting gases or particles representative of underground layers at or near the surface (analysing earth materials G01N33/24; analysing gases per se G01N) · CPC title