Composition for embryo culture

US9410120B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9410120-B2
Application numberUS-201214236534-A
CountryUS
Kind codeB2
Filing dateJul 18, 2012
Priority dateAug 3, 2011
Publication dateAug 9, 2016
Grant dateAug 9, 2016

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Abstract

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Provided is a composition for embryo culture, which contains a constitution suitable for embryo culture. Provided is a composition for embryo culture, which contains (a) a constitution shown in Table A below. TABLE A Components mM L-Alanine 0.297 ± 0.089 L-Asparagine 0.015 ± 0.005 L-Aspartic acid 0.120 ± 0.036 L-Glutamic acid 0.550 ± 0.165 Glycine 0.979 ± 0.294 L(−)-Proline 0.105 ± 0.032 L-Serine 0.176 ± 0.053 L(+)-Arginine 0.108 ± 0.032 L(−)-Cystine 0.048 ± 0.014 L-Histidine 0.053 ± 0.016 L(+)-Isoleucine 0.036 ± 0.011 L-Leucine 0.081 ± 0.024 L(+)-Lysine 0.176 ± 0.053 L-Methionine 0.022 ± 0.007 L(−)-Phenylalanine 0.045 ± 0.013 L(−)-Threonine 0.109 ± 0.033 L-Tryptophan 0.018 ± 0.005 L-Tyrosine 0.048 ± 0.014 L-Valine 0.108 ± 0.032 L-Glutamine or 0.398 ± 0.119 glutamine derivative Taurine 1.412 ± 0.424

First claim

Opening claim text (preview).

The invention claimed is: 1. A composition for an embryo culture, comprising: a mixture of the components shown in Table A below, the components being present in the concentrations shown in Table A below; and a chelator, TABLE A Components mM L-Alanine 0.297 ± 0.089 L-Asparagine 0.015 ± 0.005 L-Aspartic acid 0.120 ± 0.036 L-Glutamic acid 0.550 ± 0.165 Glycine 0.979 ± 0.294 L(−)-Proline 0.105 ± 0.032 L-Serine 0.176 ± 0.053 L(+)-Arginine 0.108 ± 0.032 L(−)-Cystine 0.048 ± 0.014 L-Histidine 0.053 ± 0.016 L(+)-Isoleucine 0.036 ± 0.011 L-Leucine 0.081 ± 0.024 L(+)-Lysine 0.176 ± 0.053 L-Methionine 0.022 ± 0.007 L(−)-Phenylalanine 0.045 ± 0.013 L(−)-Threonine 0.109 ± 0.033 L-Tryptophan 0.018 ± 0.005 L-Tyrosine 0.048 ± 0.014 L-Valine 0.108 ± 0.032 L-Glutamine or glutamine 0.398 ± 0.119 derivative Taurine 1.412 ± 0.424. 2. The composition for an embryo culture according to claim 1 , further comprising electrolytes. 3. The composition for an embryo culture according to claim 2 , further comprising organic acids and/or carbohydrates. 4. The composition for an embryo culture according to claim 3 , further comprising at least one component selected from the group consisting of pH indicators, pH adjusters, pH buffers, antibiotics, vitamins, trace metal elements, hormones, growth factors, lipids or constituents thereof, carrier proteins, extracellular matrix components, reducing substances and polymers. 5. The composition for an embryo culture according to claim 1 , wherein the glutamine derivative is glycyl-L-glutamine, L-alanyl-L-glutamine, L-leucyl-L-glutamine, L-valyl-L-glutamine or L-isoleucyl-L-glutamine. 6. The composition for an embryo culture according to claim 1 , wherein the chelator is at least one selected from the group consisting of ethyleneglycol bis tetraacetic acid, ethylene diamine tetraacetic acid, ethylene diamine diacetic acid and diethylene triamine pentaacetic acid. 7. The composition for an embryo culture according to claim 1 , wherein the composition is in the form of a sterile solution, a sterile concentrated solution or a sterile lyophilized product.

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What does patent US9410120B2 cover?
Provided is a composition for embryo culture, which contains a constitution suitable for embryo culture. Provided is a composition for embryo culture, which contains (a) a constitution shown in Table A below. TABLE A …
Who is the assignee on this patent?
Yao Tatsuma, Asayama Yuta, Matsuhisa Akio, and 1 more
What technology area does this patent fall under?
Primary CPC classification C12N5/0604. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 09 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).