Blends of polyesters containing cyclobutanediol with fluoroalkyl additives and devices made thererom

Patent metadata

Field	Value
Publication number	US-9410029-B2
Application number	US-201514615941-A
Country	US
Kind code	B2
Filing date	Feb 6, 2015
Priority date	Feb 10, 2014
Publication date	Aug 9, 2016
Grant date	Aug 9, 2016

Abstract

This invention relates to polymer compositions comprising:
(I) at least one polyester which comprises:
(a) a dicarboxylic acid component comprising:
i) 70 to 100 mole % of terephthalic acid residues; ii) 0 to 30 mole % of aromatic dicarboxylic acid residues having up to 20 carbon atoms; and iii) 0 to 10 mole % of aliphatic dicarboxylic acid residues having up to 16 carbon atoms; and
(b) a glycol component comprising 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues, wherein the total mole % of the dicarboxylic acid component is 100 mole %, the total mole % of the glycol component is 100 mole %; and wherein the inherent viscosity of the polyester is from 0.1 to 1.2 dL/g as determined in 60/40 (wt/wt) phenol/tetrachloroethane at a concentration of 0.5 g/100 ml at 25° C.; and
(II) at least one fluoroalkyl derivative.

First claim

What is claimed is:

1. A polymer composition comprising:
(I) at least one polyester which comprises:
(a) a dicarboxylic acid component comprising:
i) 70 to 100 mole % of terephthalic acid residues;
ii) 0 to 30 mole % of aromatic dicarboxylic acid residues having up to 20 carbon atoms; and
iii) 0 to 10 mole % of aliphatic dicarboxylic acid residues having up to 16 carbon atoms; and

(b) a glycol component comprising 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues,
wherein the total mole % of the dicarboxylic acid component is 100 mole %, the total mole % of the glycol component is 100 mole %; and
wherein the inherent viscosity of the polyester is from 0.1 to 1.2 dL/g as determined in 60/40 (wt/wt) phenol/tetrachloroethane at a concentration of 0.5 g/100 ml at 25° C.; and

(II) at least one fluoroalkyl derivative;
wherein said polymer composition comprises a blend of (I) and (II).

2. The polymer composition according to claim 1 comprising 1,4-cyclohexanedimethanol residues.

3. The polymer composition according to claim 2 comprising 1,4-cyclohexanedimethanol residues and ethylene glycol residues.

4. The polymer composition according to claim 2 comprising ethylene glycol residues.

5. The polymer composition of claim 2 wherein the glycol component comprises 50 to 85 mole % 1,4-cyclohexanedimethanol residues and 15 to 50 mole % 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues.

6. The polymer composition of claim 2 wherein the glycol component comprises 60 to 85 mole % 1,4-cyclohexanedimethanol residues and 15 to 40 mole % 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues.

7. The polymer composition of claim 1 wherein the acid component comprising isophthalic acid residues.

8. The polymer composition of claim 1 wherein said fluoroalkyl derivative is mixed with polyethylene.

9. The polymer composition of claim 1 wherein said fluoroalkyl derivative is present in the amount of 0.01 to 8 weight % based on the total weight percentage of said polyester and said fluroalkyl derivative.

10. The polymer composition of claim 1 wherein said fluoroalkyl derivative is present in the amount of 0.01 to 5 weight % based on the total weight percentage of said polyester and said fluroalkyl derivative.

11. The polymer composition of claim 1 or 2 which adsorbs at least 5% less fibrinogen compared to the polyester alone according to a fibrinogen enzyme-linked immunosorbent assay (ELISA) protocol, which protocol comprises the following steps: (1) incubating the polymer sample in flexural bar form in a phosphate-buffered saline solution containing 0.5 mg/mL of fibrinogen and 2% of bovine serum albumin (w/v) for 5 minutes; (2) removing unbound fibrinogen from the sample bar by washing the bar with phosphate-buffered saline having a pH of 7.3 three times; (3) incubating the sample bar in a non-animal protein blocking agent for 30 minutes at 37° C.; (4) incubating the bar in a 1 μg/mL solution of an anti-fibrinogen horseradish peroxidase antibody-conjugate in a non-animal protein-blocked microtiter plate for 60 minutes at 37° C.; (5) washing the bar four times with a diluted TBST buffer to remove excess non-specific binding of the antibody-conjugate; (6) incubating the bar with an enzyme substrate 3,3′,5,5′-tetramethylbenzidine for 60 minutes; (7) removing the bar from the microplate containing the enzyme substrate; and (8) measuring the absorbance of the enzyme substrate in the microplate well using a microplate spectrophotometer at 630 nanometers to detect conversion of the enzyme substrate to the blue product.

12. The polymer compositions of claim 2 which adsorbs from 15% to 45% less fibrinogen compared to the polyester alone.

13. The polymer compositions of claim 1 or 12 which have a coefficient of friction of less than 0.50 as measured with a Bruker™ tribometer using a 1″×1″×0.125″ plaque on a 4″×4″×0.125″ plaque under a 3 N normal load at 1.2 mm/second.

14. The polymer compositions of claim 1 or 12 which have a coefficient of friction (COF) of 0.10 to 0.50 as measured with a Bruker™ tribometer using a 1″×1″×0.125″ plaque on a 4″×4″×0.125″ plaque under a 3 N normal load at 1.2 mm/second.

15. An article of manufacture made with the polymer composition of claim 1 or 2 .

16. The article of claim 15 which is selected from a medical article, pharmaceutical article, veterinarian article, bioprocessing article, or a food article.

17. The article of claim 15 which is a medical device.

18. The article of claim 15 which is an intravenous component.

19. The polymer composition of claim 6 , wherein said fluoroalkyl derivative is present in the amount of 0.01 to 5 weight % based on the total weight percentage of said polyester and said fluroalkyl derivative.

20. The polymer composition of claim 19 , wherein said polymer exhibits a notched Izod impact strength of at least (400 J/m) 7.5 ft-lb/in at 23° C. with a 10-mil notch in a 3.2 mm (⅛-inch) thick bar determined according to ASTM D256.

Assignees

• Eastman Chem Co

Inventors

• Liu Yubiao

Classifications

• C08L67/02 Primary

  Polyesters derived from dicarboxylic acids and dihydroxy compounds (C08L67/06 takes precedence) · CPC title

• A61L31/06

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds {(A61L31/041 takes precedence)} · CPC title

• C08L101/04

  containing halogen atoms · CPC title

• C08K5/435 Primary

  Sulfonamides · CPC title

• C08G63/199

  Acids or hydroxy compounds containing cycloaliphatic rings · CPC title