Cardiac pacemaker and uses thereof

Patent metadata

Field	Value
Publication number	US-9403016-B2
Application number	US-201314387971-A
Country	US
Kind code	B2
Filing date	Mar 13, 2013
Priority date	Mar 27, 2012
Publication date	Aug 2, 2016
Grant date	Aug 2, 2016

Abstract

The invention relates to improved cardiac pacemakers and methods of use thereof. In particular the cardiac pacemakers are useful for normalizing heart rates over resting heart rates in order to condition the heart to improve overall cardiac output.

First claim

I claim:

1. An implantable device, comprising
a cardiac pacemaker having a housing, a sensor for detecting a heart rate, and a processor in the housing, connected to the sensor, that is configured to produce an output signal based on detection of a resting heart rate level by the sensor, wherein the resting heart rate is indicative of a resting patient, the output signal designed to increase the heart rate over the resting heart rate level wherein the processor is configured to produce the output signal in response to the resting heart rate in order to stimulate a remodeling of the heart muscle that results in a heart chamber enlargement in the patient.

2. The implantable device of claim 1 , wherein the pacemaker includes a motion or physical activity detector.

3. The implantable device of claim 1 , wherein the pacemaker includes a position detector.

4. The implantable device of claim 1 , wherein the pacemaker is configured to have night function which involves the processor configured to produce the output signal in response to detection by the sensor of a sleeping patient.

5. The implantable device of claim 1 , wherein the pacemaker has a remote monitoring device.

6. The implantable device of claim 1 , wherein the pacemaker comprises a housing, wherein the sensor extend from the housing.

7. The implantable device of claim 1 , wherein the sensor has an input circuit that receives a signal representative of a heartbeat sensed within a heart as a function of time.

8. A method, comprising
increasing a heart rate in a subject, wherein the subject is at rest, using the pacemaker of claim 1 , wherein the pacemaker detects a resting state heart rate, and wherein in response to the resting heart rate the pacemaker delivers a signal to stimulate a heart chamber enlargement in the subject, in order to promote remodeling of the heart tissue.

9. The method of claim 8 , wherein the subject is not otherwise indicated for a currently accepted treatment with a pacemaker.

10. The method of claim 9 , wherein the subject is obese.

11. The method of claim 9 , wherein the subject has high blood pressure and/or heart failure with preserved ejection fraction or an impaired ability to relax the heart muscle.

12. The method of claim 8 , wherein the pacemaker includes a motion or physical activity detector and wherein when the pacemaker detects movement or physical activity of the subject, the heart rate is reduced.

13. The method of claim 8 , wherein the subject at rest is sleeping.

Assignees

• The Univ Of Vermont And State Agricultural College

Inventors

• Meyer Markus

Classifications

• A61N1/36507

  controlled by gradient or slope of the heart potential · CPC title

• A61N1/36542 Primary

  controlled by body motion, e.g. acceleration · CPC title

• A61N1/365

  controlled by a physiological parameter, e.g. heart potential {(evoked response A61N1/371)} · CPC title

• A61N1/36535

  controlled by body position or posture · CPC title

• A61N1/36585 Primary

  controlled by two or more physical parameters · CPC title