Methods for in vivo identification of cancer initiating cells by multimodality reporter gene imaging
US-9220793-B2 · Dec 29, 2015 · US
Probes and methods of imaging a bacterial infection
US9402925B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9402925-B2 |
| Application number | US-201414204402-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 11, 2014 |
| Priority date | Mar 12, 2013 |
| Publication date | Aug 2, 2016 |
| Grant date | Aug 2, 2016 |
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- Title
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Abstract
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Embodiments of the present disclosure provide for labeled probes such as labeled maltose probes and labeled acarbose probes, methods of making labeled probes, pharmaceutical compositions including labeled probes, methods of using labeled probes, methods of diagnosing, localizing, monitoring, and/or assessing bacterial infections, using labeled probes, kits for diagnosing, localizing, monitoring, and/or assessing bacterial infections, using labeled probes, and the like.
First claim
Opening claim text (preview).
We claim at least the following: 1. A method of imaging a bacterial infection in a subject comprising the following steps: administering to the subject a labeled probe selected from the group consisting of: wherein R1 is a radiolabel, wherein the radiolabel is selected from the group consisting of: 18 F, 125 I, 124 I, 131 I, 123 I, 32 Cl, 33 Cl, 34 Cl, 74 Br, 75 Br, 76 Br, 77 Br, and 78 Br; imaging at least a portion of the subject; and detecting the labeled probe, wherein the location of the labeled probe corresponds to bacterial infection. 2. The method of claim 1 , wherein the labeled probe has one of the following structures: 3. The method of claim 1 , wherein the labeled probe is selected from the group consisting of: 4. The method of claim 1 , further comprising repeating the steps of claim 1 periodically to monitor the progress of a bacterial infection in the subject. 5. The method of claim 4 , wherein monitoring includes monitoring the dimensions of the location corresponding to the bacterial infection.
Assignees
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Classifications
- A61K51/0491Primary
Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers · CPC title
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Frequently asked questions
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- What does patent US9402925B2 cover?
- Embodiments of the present disclosure provide for labeled probes such as labeled maltose probes and labeled acarbose probes, methods of making labeled probes, pharmaceutical compositions including labeled probes, methods of using labeled probes, methods of diagnosing, localizing, monitoring, and/or assessing bacterial infections, using labeled probes, kits for diagnosing, localizing, monitoring…
- Who is the assignee on this patent?
- Univ Leland Stanford Junior, The Board Of Trustees Of The Leland Stanford Junio
- What technology area does this patent fall under?
- Primary CPC classification A61K51/0491. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Aug 02 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).