Pyrrolobenzodiazepines and conjugates thereof
US-2016031887-A1 · Feb 4, 2016 · US
Pyrrolobenzodiazepines as unsymmetrical dimeric PBD compounds for inclusion in targeted conjugates
US9399641B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9399641-B2 |
| Application number | US-201214346006-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 20, 2012 |
| Priority date | Sep 20, 2011 |
| Publication date | Jul 26, 2016 |
| Grant date | Jul 26, 2016 |
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Abstract
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A compound with the formula I wherein: R 2 is of formula II where Q is selected from OH, SH and NR N , and R N is selected from H, methyl and ethyl, as well as drug-linkers and drug-conjugates made from this compound.
First claim
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The invention claimed is: 1. A compound with the formula I: wherein: R 2 is of formula II: where Q is selected from OH, SH and NHR N , and R N is selected from H, methyl and ethyl; when there is a double bond present between C2′ and C3′, R 12 is select…
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Frequently asked questions
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- What does patent US9399641B2 cover?
- A compound with the formula I wherein: R 2 is of formula II where Q is selected from OH, SH and NR N , and R N is selected from H, methyl and ethyl, as well as drug-linkers and drug-conjugates made from this compound.
- Who is the assignee on this patent?
- Medimmune Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07D519/00. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).