Compositions for regenerating defective or absent myocardium
US-9199001-B2 · Dec 1, 2015 · US
US9394515B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9394515-B2 |
| Application number | US-201414184002-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 19, 2014 |
| Priority date | Feb 22, 2013 |
| Publication date | Jul 19, 2016 |
| Grant date | Jul 19, 2016 |
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Methods for increasing breast muscle weight in poultry are disclosed herein. These methods can include delivery of compositions via in ovo administration. The methods disclosed herein also encompass the delivery of proteins. The methods disclosed herein are effective for increasing breast muscle weight in poultry, both in the embryo, and at slaughter age.
Opening claim text (preview).
The invention claimed is: 1. A method of increasing muscle mass in a chicken, comprising the steps of: a) administering a composition comprising between about 10-40 ng of Fibroblast Growth Factor-2; and a pharmaceutically acceptable carrier in ovo to an embryonated chicken egg between embryonal day 0 and embryonal day 4; and b) incubating said embryonated chicken egg until hatch; wherein said Fibroblast Growth Factor-2 is selected from SEQ ID NO.1 or SEQ ID NO. 3. 2. The method of claim 1 wherein said administration occurs on about embryonal day 0. 3. The method of claim 1 wherein said administration occurs on about embryonal day 1 (ED1). 4. The method of claim 1 wherein said administration occurs on about embryonal day 2 (ED2). 5. The method of claim 1 wherein said administration occurs on about embryonal day 3 (ED3). 6. The method of claim 1 wherein said administration occurs on about embryonal day 4 (ED4).
Solutions {(composition of solutions A61K47/00)} · CPC title
Fibroblast growth factor [FGF] · CPC title
Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2 {(insulin-like growth factor binding protein A61K38/1754)} · CPC title
Polymeric derivatives, e.g. peptides or proteins · CPC title
Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2 · CPC title
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