Signal peptides for increased protein secretion
US-2024141363-A1 · May 2, 2024 · US
Deimmunized gelonin molecules and therapies
US9388397B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9388397-B2 |
| Application number | US-201414767745-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 14, 2014 |
| Priority date | Feb 15, 2013 |
| Publication date | Jul 12, 2016 |
| Grant date | Jul 12, 2016 |
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Abstract
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Recombinant gelonin polypeptides with decreased antigenicity are provided. Cell-targeted constructs comprising said recombinant gelonin polypeptides are also provided. Such constructs can be used in methods for targeted cell killing, such as for treatment of cell proliferative diseases (e.g., cancer).
First claim
Opening claim text (preview).
What is claimed is: 1. A recombinant polypeptide comprising a recombinant gelonin toxin according to SEQ ID NO: 1 or SEQ ID NO: 2. 2. The polypeptide of claim 1 , comprising the sequence of SEQ ID NO: 1. 3. The polypeptide of claim 1 , comprising the sequence of SEQ ID NO: 2. 4. The polypeptide of claim 1 , wherein the polypeptide is fused or conjugated to a second polypeptide. 5. The polypeptide of…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12N9/24Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US9388397B2 cover?
- Recombinant gelonin polypeptides with decreased antigenicity are provided. Cell-targeted constructs comprising said recombinant gelonin polypeptides are also provided. Such constructs can be used in methods for targeted cell killing, such as for treatment of cell proliferative diseases (e.g., cancer).
- Who is the assignee on this patent?
- Res Dev Foundation
- What technology area does this patent fall under?
- Primary CPC classification C12N9/24. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jul 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).