Lactobacillus paracasei strain
US-12152232-B2 · Nov 26, 2024 · US
US9387229B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-9387229-B2 |
| Application number | US-201114361565-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 30, 2011 |
| Priority date | Nov 30, 2011 |
| Publication date | Jul 12, 2016 |
| Grant date | Jul 12, 2016 |
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The invention relates to reuterin-producing strains of Lactobacillus brevis . These strains are useful in particular for the treatment or the prevention of conditions resulting from Helicobacter pylori infection.
Opening claim text (preview).
The invention claimed is: 1. A reuterin-accumulating Lactobacillus brevis strain that is the Lactobacillus brevis strain deposited with the CNCM (Collection Nationale De Cultures De Microorganismes) under Accession number I-4431. 2. A method of producing reuterin comprising the steps of: (a) culturing the Lactobacillus brevis strain of claim 1 under conditions sufficient to produce reuterin and (b) recovering the reuterin produced by the culture in step (a). 3. A nutritional composition comprising the Lactobacillus strain of claim 1 . 4. The composition according to claim 3 , comprising at least 10 5 cfu, per gram dry weight, of the Lactobacillus brevis strain. 5. The composition of claim 3 , wherein the composition is a dairy product. 6. The composition of claim 3 , wherein the composition is a fermented dairy product. 7. A pharmaceutical composition comprising the Lactobacillus brevis strain of claim 1 . 8. A method of treating an H. pylori infection in a subject in need thereof comprising administering to the subject the pharmaceutical composition according to claim 7 in an amount effective to treat the H. pylori infection. 9. The method of claim 8 , wherein the subject is suffering from a H. pylori infection.
Antibacterial agents · CPC title
for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants · CPC title
Bacteria or derivatives thereof, e.g. probiotics · CPC title
Lactobacilli, e.g. L. acidophilus or L. brevis · CPC title
Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title
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