Reuterin-producing Lactobacillus brevis

US9387229B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-9387229-B2
Application numberUS-201114361565-A
CountryUS
Kind codeB2
Filing dateNov 30, 2011
Priority dateNov 30, 2011
Publication dateJul 12, 2016
Grant dateJul 12, 2016

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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Abstract

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The invention relates to reuterin-producing strains of Lactobacillus brevis . These strains are useful in particular for the treatment or the prevention of conditions resulting from Helicobacter pylori infection.

First claim

Opening claim text (preview).

The invention claimed is: 1. A reuterin-accumulating Lactobacillus brevis strain that is the Lactobacillus brevis strain deposited with the CNCM (Collection Nationale De Cultures De Microorganismes) under Accession number I-4431. 2. A method of producing reuterin comprising the steps of: (a) culturing the Lactobacillus brevis strain of claim 1 under conditions sufficient to produce reuterin and (b) recovering the reuterin produced by the culture in step (a). 3. A nutritional composition comprising the Lactobacillus strain of claim 1 . 4. The composition according to claim 3 , comprising at least 10 5 cfu, per gram dry weight, of the Lactobacillus brevis strain. 5. The composition of claim 3 , wherein the composition is a dairy product. 6. The composition of claim 3 , wherein the composition is a fermented dairy product. 7. A pharmaceutical composition comprising the Lactobacillus brevis strain of claim 1 . 8. A method of treating an H. pylori infection in a subject in need thereof comprising administering to the subject the pharmaceutical composition according to claim 7 in an amount effective to treat the H. pylori infection. 9. The method of claim 8 , wherein the subject is suffering from a H. pylori infection.

Assignees

Inventors

Classifications

  • Antibacterial agents · CPC title

  • for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants · CPC title

  • Bacteria or derivatives thereof, e.g. probiotics · CPC title

  • A61K35/747Primary

    Lactobacilli, e.g. L. acidophilus or L. brevis · CPC title

  • Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

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What does patent US9387229B2 cover?
The invention relates to reuterin-producing strains of Lactobacillus brevis . These strains are useful in particular for the treatment or the prevention of conditions resulting from Helicobacter pylori infection.
Who is the assignee on this patent?
Garault Peggy, Quere Gaelle, Bourdet-Sicard Raphaelle, and 1 more
What technology area does this patent fall under?
Primary CPC classification A61K35/747. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jul 12 2016 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).